We characterized 2 clusters of blastomycosis cases in Minnesota, USA, using whole-genome sequencing and single-nucleotide polymorphism analyses. Blastomyces gilchristii was confirmed as the cause of infection. Genomic analyses corresponded with epidemiologic findings for cases of B. gilchristii infections, demonstrating the utility of genomic methods for future blastomycosis outbreak investigations.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423935 | PMC |
http://dx.doi.org/10.3201/eid2809.220392 | DOI Listing |
Clin Infect Dis
October 2024
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
G3 (Bethesda)
November 2024
Microbiology and Laboratory Services, Public Health Ontario, 661 University Avenue, Toronto, ON M5G 1M1, Canada.
Using phylogenomic analysis, we provide genomic epidemiology analysis of a large blastomycosis outbreak in Ontario, Canada, caused by Blastomyces gilchristii. The outbreak occurred in a locale where blastomycosis is rarely diagnosed, signaling a possible shift in geographically associated incidence patterns. Results elucidated fungal population genetic structure, enhancing understanding of the outbreak.
View Article and Find Full Text PDFMed Mycol
January 2024
Integrated Research and Development Laboratory, Marshfield Clinic Research Institute. Marshfield, WI, USA.
Med Mycol
December 2023
Michigan State University College of Human Medicine, Western Upper Peninsula Health Department, Hancock, Michigan, United States.
A large outbreak of blastomycosis among paper mill workers in Escanaba, Michigan began with the first cases reported on February 28, 2023 and expanded to 120 cases. Analysis of baseline regional data and the data collected during this unprecedented outbreak provide insight on the outbreak's unique characteristics. The Michigan Disease Surveillance System provided descriptive and outcome data on blastomycosis cases in the Upper Peninsula from 2007 through 2022 and the 2023 outbreak.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!