Because of a desire to provide the most suitable treatment for hemodialysis patients, psychological, physical and social problems influencing psychiatric conditions of the patients were studied. One hundred hemodialysis inpatients were compared in each group divided by their characteristics, i.e. age, presence of family problems, occupation, physical complications and their character traits. Psychiatric conditions were most favorable between 3 and 12 months after the introduction of hemodialysis, whereas in other hemodialysis terms depression was noticed in more than half of the subjects. In most of the patients, irritation and anger, and loss of brightness and sympathy were observed during the first 3 months or later than 12 months after the introduction of therapy, respectively. Some of the patients required explanations about the necessity of hemodialysis repeatedly and/or through consecutive psychotherapeutic interviews. This study suggested that a poor outcome of psychological conditions after the introduction of hemodialysis was indicated by the presence of family problems, symptoms of physical origin, the absence of full-time work, having a young child or children, age in the 20-40 year group, B and E type character traits classified by the Yatabe and Gilford test and a long duration of therapy.
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http://dx.doi.org/10.1111/j.1440-1819.1986.tb03170.x | DOI Listing |
Child Adolesc Psychiatry Ment Health
January 2025
Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
Background: Primary school students struggling with mental health are less likely than high school students to access mental health care, due to barriers such as mental health stigma and low mental health literacy among children and parents. The near universal reach of schools offers a potential avenue to increase access to mental health care through early identification. The potential risks of this approach also need to be understood.
View Article and Find Full Text PDFBMC Psychiatry
January 2025
Clinical Research Development Center, Imam Khomeini and Mohammad Kermanshahi and Farabi Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Background: Glial cell line-derived neurotrophic factor (GDNF) has emerged as a potential biomarker for schizophrenia (SCZ). However, GDNF levels remain unclear in affected individuals compared to healthy controls. Therefore, we aimed to calculate a pooled estimate of GDNF levels in patients with SCZ in comparison with healthy controls.
View Article and Find Full Text PDFMol Psychiatry
January 2025
Department of Psychological Medicine and Clinical Neuroscience, Cardiff University, United Kingdom and UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.
In this perspective we draw together the data from the genome wide association studies for Alzheimer's disease, Parkinson's disease and the tauopathies and reach the conclusion that in each case, most of the risk loci are involved in the clearance of the deposited proteins: in Alzheimer's disease, the microglial removal of Aβ, in the synucleinopathies, the lysosomal clearance of synuclein and in the tauopathies, the removal of tau protein by the ubiquitin proteasome. We make the point that most loci identified through genome wide association studies are not strictly pathogenic but rather relate to failures to remove age related damage. We discuss these issues in the context of copathologies in elderly individuals and the prediction of disease through polygenic risk score analysis at different ages.
View Article and Find Full Text PDFEpidemiol Psychiatr Sci
January 2025
Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, Center for Global Mental Health, King's College London, London, UK.
In low- and middle-income countries, fewer than 1 in 10 people with mental health conditions are estimated to be accurately diagnosed in primary care. This is despite more than 90 countries providing mental health training for primary healthcare workers in the past two decades. The lack of accurate diagnoses is a major bottleneck to reducing the global mental health treatment gap.
View Article and Find Full Text PDFRinsho Shinkeigaku
January 2025
Department of Internal Medicine IV, Division of Neurology, Osaka Medical and Pharmaceutical University Faculty of Medicine.
In an 81-year-old man, brain diffusion-weighted MRI revealed punctate high-intensity lesions in the bilateral frontal cortex. Three months later, these lesions had extended into the cerebral cortices. Six months after the original MRI, the patient developed cognitive decline.
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