Alcohol use disorder is a complex disorder that is influenced by genetic factors. The non-synonymous single-nucleotide polymorphism (SNP) rs1799971 in exon 1 in opioid receptor was extensively studied in patients with alcohol dependence with mixed findings. Moreover, studies showed that opioid receptor polymorphism might play a role in the pathophysiology of schizophrenia. Our results suggest that rs1799971 SNP is not significantly associated with alcohol dependence in our sample of Schizophrenia patients of European ancestry.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387363 | PMC |
http://dx.doi.org/10.1097/cxa.0000000000000069 | DOI Listing |
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