Concerns have been raised recently about takotsubo cardiomyopathy (TCM) after receiving COVID-19 vaccines, particularly the messenger RNA (mRNA) vaccines. The goal of this study was to compile case reports to provide a comprehensive overview of takotsubo cardiomyopathy (TCM) associated with COVID-19 vaccines. A systematic literature search was conducted in PubMed, Scopus, Embase, Web of Science, and Google Scholar between 2020 and June 1, 2022. The study included individuals who developed cardiac takotsubo cardiomyopathy from receiving COVID-19 vaccinations. Ten studies, including 10 cases, participated in the current systematic review. The mean age was 61.8 years; 90 % were female, while 10 % were male. 80 % of the patients received the mRNA COVID-19 vaccine, while 20 % received other types. In addition, takotsubo cardiomyopathy (TCM) occurred in 50 % of patients receiving the first dose and another 40 % after the second dose of COVID-19 vaccines. Moreover, the mean number of days to the onset of symptoms was 2.62 days. All cases had an elevated troponin test and abnormal ECG findings. The left ventricular ejection fraction (LVEF) was lower than 50 % in 90 % of patients. In terms of the average length of hospital stay, 50 % stayed for 10.2 days, and all cases recovered from their symptoms. In conclusion, takotsubo (stress) cardiomyopathy (TCM) complications associated with COVID-19 vaccination are rare but can be life-threatening. Chest pain should be considered an alarming symptom, especially in those who have received the first and second doses of the COVID-19 vaccine.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381427 | PMC |
http://dx.doi.org/10.1016/j.ijcha.2022.101108 | DOI Listing |
Eur Heart J Case Rep
January 2025
Department of Cardiology, Christian Medical College, New Arcot Road, Vellore 632517, India.
Background: Granulomatosis with polyangiitis (GPA) is an autoimmune multisystem disorder characterized by small vessel vasculitis with granulomatous inflammation. In this report, we describe a unique case of GPA who presented with complete heart block (CHB) and developed complications due to intracranial large vessel involvement.
Case Summary: A 47-year-old gentleman presented with CHB with a background history of arthralgia and blood-tinged nasal discharge.
Cureus
November 2024
Anesthesia and Critical Care, Mohammed VI University Hospital, Tangier, MAR.
Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is a rare condition in children that causes acute, severe, but often reversible systolic dysfunction of the left ventricle. Physical trauma is a recognized trigger, although distinguishing TTC from myocardial contusion in pediatric trauma cases can be challenging due to overlapping clinical features. We present the case of a six-year-old boy involved in a high-impact motor vehicle collision.
View Article and Find Full Text PDFThis case emphasizes the rare occurrence of Takotsubo cardiomyopathy (TTC) in a patient with moderate coronary artery disease (CAD), highlighting the complexity of diagnosis and management. Clinicians should maintain a high index of suspicion for TTC in patients with CAD, especially when echocardiographic findings suggest apical ballooning. Balancing therapies for both conditions is essential.
View Article and Find Full Text PDFLiver Transpl
December 2024
University of Michigan and Michigan Medicine, Department of Internal Medicine, Division of Cardiovascular Medicine, Ann Arbor, Michigan, USA.
Int J Cardiovasc Imaging
December 2024
Cardiothoracic Imaging, Department of Radiology, University of Washington, Seattle, USA.
Stress/Takotsubo cardiomyopathy (TCM) is a transient regional left ventricular (LV) systolic dysfunction, often mimicking acute myocardial infarction with normal coronary arteries. Rarely TCM can mimic hypertrophic cardiomyopathy (HCM). We describe a case where TCM presented with LV hypertrophy (LVH) and left ventricular outflow tract obstruction (LVOTO) which resolved on follow-up.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!