AI Article Synopsis
- - Mitral valve prolapse (MVP) affects 1-3% of people and can increase the risk of sudden cardiac death in certain patients due to fibrotic changes in the heart's papillary muscles.
- - ECG signs of MVP include ST-segment depression, T wave inversion, and premature ventricular contractions, while echocardiography can detect MVP and mitral annular disjunction, which is linked to poorer outcomes.
- - High-risk MVP patients may need further evaluation, and treatments like catheter ablation or mitral valve repair can help lower the risk of dangerous heart rhythms; some may also qualify for an implantable cardioverter-defibrillator (ICD).
Article Abstract
Mitral valve prolapse (MVP) is a common condition present in 1-3% of the population. There has been evidence that a subset of MVP patients is at higher risk of sudden cardiac death. The arrhythmogenic mechanism is related to fibrotic changes in the papillary muscles caused by the prolapsing valve. ECG features include ST-segment depression, T wave inversion or biphasic T waves in inferior leads, and premature ventricular contractions arising from the papillary muscles and the fascicular system. Echocardiography can identify MVP and mitral annular disjunction, a feature that has significant negative prognostic value in MVP. Cardiac MRI is indicated for identifying fibrosis. Patients with high-risk features should be referred for further evaluation. Catheter ablation and mitral valve repair might reduce the risk of malignant arrhythmia. MVP patients with high-risk features and clinically documented ventricular arrhythmia may also be considered for an ICD.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376835 | PMC |
| http://dx.doi.org/10.15420/aer.2021.28 | DOI Listing |
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