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Efficacy of manual acupuncture, electro-acupuncture, and warm acupuncture for knee osteoarthritis: study protocol for a randomized controlled trial. | LitMetric

AI Article Synopsis

  • - This study plans to compare the effectiveness of manual acupuncture (MA), electro-acupuncture (EA), and warm acupuncture (WA) for treating knee osteoarthritis (KOA) through a randomized controlled trial involving 200 participants.
  • - Participants will be divided into four groups: MA, EA, WA, and a sham acupuncture (SA) group, with treatments administered daily for four weeks.
  • - The primary measure of efficacy will be changes in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) after four weeks, along with several secondary outcome measures related to pain and quality of life.

Article Abstract

Background: Acupuncture is one of the most popular complementary and alternative treatments for knee osteoarthritis (KOA). There are many methods of acupuncture in the treatment of KOA, and the effects are different. According to our clinical observations and researches, it is found that manual acupuncture (MA), electro-acupuncture (EA), and warm acupuncture (WA) are used more frequently in the treatment of KOA, and the curative effects are satisfactory. However, there is currently a lack of efficacy comparison of efficacy between different acupuncture treatments, as well as a lack of standardized clinical research on the acupuncture treatment of KOA. Therefore, we will carry out a high-quality clinical randomized controlled trial to research the effect laws of MA, EA, and WA on KOA.

Methods/design: A total of 200 eligible participants with KOA will be randomly assigned to group A, B, C, or D in a ratio of 1:1:1:1. Patients in group A will receive MA, while those in group B, group C, and group D will be treated with EA, WA, and sham acupuncture (SA), respectively. Patients will be treated with acupuncture once a day, 30 min per session, 5 sessions per week for 4 weeks. The primary outcome is the change of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at week 4. The secondary outcomes include WOMAC, visual analog scale (VAS), Arthritis Quality of Life Measurement Scale Simplified Scale (AIMS2-SF), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), and Credibility/Expectancy Questionnaire. The evaluation will be performed at baseline and weeks 4, 8, and 12 respectively after randomization.

Discussion: This is a randomized controlled trial. We will observe the clinical effect of MA, EA, and WA on KOA to research the effect laws of these three acupuncture treatments on KOA and set up standardized treatment programs for acupuncture for KOA.

Trial Registration: China Clinical Trials Registry ChiCTR2100049526. Registered on August 2, 2021.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392363PMC
http://dx.doi.org/10.1186/s13063-022-06653-7DOI Listing

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