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Article Synopsis
- Hypochlorous acid (HClO) is a reactive oxygen species produced in mitochondria, and its high levels are associated with various diseases, making its detection crucial in medicine.
- A new dual-modality probe called MB-ClO has been developed, which uses near-infrared fluorescence (NIRF) and photoacoustic (PA) imaging techniques to accurately and sensitively detect HClO in biological systems.
- MB-ClO shows low toxicity and good water solubility, has a fast response time, and has been successfully tested in a mouse model of rheumatoid arthritis, highlighting its potential for biomedical applications.
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