AI Article Synopsis

  • Blumea lacera has garnered scientific interest due to its diverse biological activities and traditional medicinal uses, prompting a study on its bioactive compounds.
  • The research revealed varying levels of total phenolics and flavonoids across different plant tissues, with old leaves having the highest amounts.
  • Key compounds like rosmarinic acid, quercetin, and kaempferol were identified, and the plant exhibited strong enzyme inhibition activities, indicating its potential for treating obesity, neurological issues, and skin pigmentation disorders.

Article Abstract

Blumea lacera (Burm. f.) DC. is attracting scientific interest due to the diverse biological activities of its various parts and its use in folk medicine. The present study was undertaken to investigate the tissue-specific differential expression pattern of its total bioactive compounds. The study was further extended to whole plant phenolics profiling, in vitro enzyme inhibition activities, followed by in silico enzyme inhibition analysis to assess its potential as herbal medicine. The amount of total phenolics in different tissues was followed in decreasing order as old leaf, flower bud, root, young leaf, flower, old stem, and young stem, while that for the flavonoids was old leaf, root, young leaf, flower bud, flower, young stem, and old stem. This study identified rosmarinic acid, quercetin, and kaempferol in this plant for the first time. The solvent extracts demonstrated strong inhibition of lipase and tyrosinase activity, along with varying degrees of inhibition of acetylcholinesterase and butyrylcholinesterase activity. Among the detected compounds, ten displayed strong in silico binding affinities with the tested enzymes. The findings provide a new insight into further investigation of the medicinal potential of this species against obesity, neurological disorders, and aberrant skin color.

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbdv.202200282DOI Listing

Publication Analysis

Top Keywords

leaf flower
12
blumea lacera
8
lacera burm
8
enzyme inhibition
8
flower bud
8
root young
8
young leaf
8
young stem
8
polyphenols profile
4
profile enzyme
4

Similar Publications

A review on : phytochemical and biological aspects.

Nat Prod Res

December 2024

Department of Chemistry, Faculty of Science, Birzeit University, Birzeit, Ramallah, Palestine.

is a wild edible, parietal, unisexual, perennial plant that grows in various parts of the Middle East, and frequently used in traditional Arabic Palestinian herbal medicine. The present review summarises information concerning including background information, historical records, phytochemical components, and biological activity which represents an important tool for further research studies. is thought to contain a wealth of rich bioactive compounds, such as terpinoids, polyphenols, flavonoids, and alkaloids.

View Article and Find Full Text PDF

2-methylguanosine is an eukaryote-specific modified nucleoside in transfer RNAs, and mG10 is catalyzed by Trm11-Trm112 protein complex in eukaryotic tRNAs. Here, we show that loss-of-function mutation of the Arabidopsis Trm11 homolog AtTRM11 resulted in mG deficiency associated with disturbed ribosome assembly and overall transcriptome changes, including genes involved in flowering regulation and plant-pathogen interaction. The attrm11 mutant showed phenotypes of enlarged rosette leaves and early flowering, as well as enhanced resistance to Pseudomonas bacterial infection.

View Article and Find Full Text PDF

Abiotic and biotic factors interact to influence phenotypic evolution; however, identifying the causal agents of selection that drive the evolution and expression of traits remains challenging. In a field common garden, we manipulated water availability and herbivore abundance across three years, and evaluated clinal variation in functional traits and phenology, plasticity, local adaptation, and selection using diverse accessions of the perennial forb, Boechera stricta. Consistent with expectations, drought stress exacerbated damage from herbivores.

View Article and Find Full Text PDF

Background: Safflower thrives in dry environments but faces difficulties with flowering in wet and rainy summers. Flavonoids play a role in flower development and can potentially alleviate these challenges. Furthermore, the FLOWERING LOCUS T (FT) family of phosphatidylethanolamine-binding protein (PEBP) genes play a crucial role in the photoperiodic flowering pathway.

View Article and Find Full Text PDF

Melatonin (MT) can improve plant resistance and fruit quality. The mechanism by which MT affects soluble sugar and organic acids accumulation in drupe fruits is not clear. In this study, 100 µmol/L MT was sprayed on the leaves of plum trees at the second stage of rapid fruit expansion (90 and 97 d after flowering), and the effects of MT on plum fruit quality and its effects on the soluble sugar-organic acid metabolism were investigated.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: