Characterisation of indole alkaloids and phenolic acids from wild mushroom and its chemical profiles compared with other Sanghuang mushrooms.

Nat Prod Res

Multidisciplinary Research Unit of Pure and Applied Chemistry, Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahasarakham University, Khamriang, Maha Sarakham, Thailand.

Published: December 2023

Two new indole alkaloids, 1-methylindole-7-methoxy-3-carboxaldehyde () and 7-methoxyindole-3-carboxaldehyde (), together with 7-methoxyindole-3-carboxylic acid methyl ester ( and 1-methylindole-3-carbaldehyde () were isolated from the fruiting bodies of wild Sanghuang mushroom (TL663). TLC, H-NMR and LC-MS chemical profiles of this mushroom compared with other three genera of wild Sanghuang mushroom extracts were investigated. The TLC, H-NMR and LC-MS profiles of TL663 and (SS664) were similar and significantly different from other mushrooms. These two samples indicated the same TLC chromatograms by showing prominent bands of - when observed under UV 254 nm and having sharp aldehyde proton signals of 3-carboxaldehyde indole type in H-NMR spectra. From LC-MS analyses, peaks of isolated compounds - and indole-3-carboxaldehyde () in TL663 extract and peaks of protocatechuic acid (), caffeic aldehyde (), caffeic acid () and 3,4-dihydroxybenzalacetone () phenolic acids in TL663 fraction were identified.

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http://dx.doi.org/10.1080/14786419.2022.2112036DOI Listing

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