Fucoxanthin (FX) is a special carotenoid having an allenic bond in its structure. FX is extracted from a variety of algae and edible seaweeds. It has been proved to contain numerous health benefits and preventive effects against diseases like diabetes, obesity, liver cirrhosis, malignant cancer, etc. Thus, FX can be used as a potent source of both pharmacological and nutritional ingredient to prevent infectious diseases. In this review, we gathered the information regarding the current findings on antimicrobial, antioxidant, anti-inflammatory, skin protective, anti-obesity, antidiabetic, hepatoprotective, and other properties of FX including its bioavailability and stability characteristics. This review aims to assist further biochemical studies in order to develop further pharmaceutical assets and nutritional products in combination with FX and its various metabolites.
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http://dx.doi.org/10.3389/fphar.2022.929442 | DOI Listing |
Nutrients
December 2024
Facultad de Ciencias Biológicas, Instituto de Biotecnología, Universidad Autónoma de Nuevo León, Campus Ciudad Universitaria, Av. Universidad S/N, San Nicolás de los Garza 66455, Mexico.
Plants and algae harbor diverse molecules with antioxidant activity and have been demonstrated to directly inhibit cancer cell growth and mitigate the oxidative damage associated with certain antitumor therapies. While antioxidant supplementation, either alone or in combination with chemotherapy, has shown promise in improving quality of life, further research is needed to explore the effects of antioxidant combinations on specific cancer cell lines. In this study, the in vitro cytotoxic and apoptotic properties of natural compounds derived from plants and algae, as well as certain dietary supplements, were investigated against various human cancer cell lines, including bone, leukemia, colorectal, breast, and prostate cancers.
View Article and Find Full Text PDFLife (Basel)
November 2024
REQUIMTE/LAQV, ISEP, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal.
This study aimed at optimizing carotenoid extraction using the macroalga (L.) S.F.
View Article and Find Full Text PDFHeliyon
January 2025
FRHPHM Division, ICAR-Central Institute of Fisheries Education, Yari Road Campus, Versova, Mumbai, 400 061, India.
Food Chem
December 2024
Centre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal; IBS, Institute of Science and Innovation for Bio-Sustainability, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. Electronic address:
Microalgae are emerging as valuable sources of bioactive compounds. This study evaluates hexane extracts from Thalassiosira sp. and Raphidonema sp.
View Article and Find Full Text PDFInt J Nanomedicine
December 2024
Department of Orthodontics, Dental Research Institute, Pusan National University, Yangsan, 50612, South Korea.
Purpose: To evaluate the effects of fucosterol and fucoxanthin on ultimate microtensile strength (µUTS), dentin collagen cross-linking, erosion resistance, and matrix metalloproteinase (MMP) inhibition.
Methods: Dentin beams and slices were prepared from extracted human teeth and treated with concentrations of 50 µg/mL, 100 µg/mL, and 200 µg/mL of fucosterol and fucoxanthin. Fourier-transform infrared spectroscopy (FTIR) was used to analyze collagen cross-linking.
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