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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556748 | PMC |
| http://dx.doi.org/10.1038/s41386-022-01419-w | DOI Listing |
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Theranostics, Theragnostics, or Iama-gnostics?
Hell J Nucl Med
December 2024
Retired Consultant Medical Oncologist , Formerly, Charing Cross Hospital, London, U.K.
Many reputable medical journals, including The Lancet and the BMJ, have adopted the term "Theranostics". Under the alternative term "Theragnostics", PubMed currently registers 1207 articles. Both terms encountered by the reader for the first time are puzzling and largely meaningless, if not confusing.
View Article and Find Full Text PDFInhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson's Disease.
bioRxiv
November 2024
Kavli Institute for Fundamental Neuroscience, UCSF, San Francisco, CA 94158, USA.
Healthy action selection relies on the coordinated activity of striatal direct and indirect pathway neurons. In Parkinson's disease (PD), in which loss of midbrain dopamine neurons is associated with progressive motor and cognitive deficits, this coordination is disrupted. Dopamine replacement therapy can remediate motor symptoms, but can also cause impulse control disorder (ICD), which is characterized by pathological gambling, hypersexuality, and/or compulsive shopping.
View Article and Find Full Text PDFExamining relationships among NODDI indices of white matter structure in prefrontal cortical-thalamic-striatal circuitry and OCD symptomatology.
Transl Psychiatry
October 2024
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Obsessive-compulsive disorder is a psychiatric disorder characterized by intrusive thoughts and repetitive behaviors. There are two prominent features: Harm Avoidance (HA) and Incompleteness (INC). Previous resting-state studies reported abnormally elevated connectivity between prefrontal cortical (PFC) and subcortical regions (thalamus, striatum) in OCD participants.
View Article and Find Full Text PDFWithin-session chasing of losses and wins in an online eCasino.
Sci Rep
September 2024
Department of Psychology, University of British Columbia, Vancouver, BC, Canada.
Chasing refers to the escalation of betting behaviour. It is conventionally seen when losing but can also be seen after wins. Diagnostic and screening items for gambling problems describe chasing as returning 'another day' to gamble.
View Article and Find Full Text PDFGetting even: chasing behavior, decision-making, and craving in habitual gamblers.
BMC Psychol
August 2024
Department of Psychology, University of Campania Luigi Vanvitelli, Viale Ellittico, 31, Caserta, 81100, Italy.
Background: Dysfunctional decision-making and intense craving represent pivotal aspects across all addictive behaviors, notably evident in gambling addiction where these factors significantly shape chasing behavior-continuing gambling to recoup losses-indicative of problematic gambling. This study explores the correlation between chasing behavior, craving, affective decision-making, decision-making styles, and gambling severity among habitual Italian gamblers.
Methods: One hundred and sixty-six participants from diverse gambling venues completed assessments including the South Oaks Gambling Screen (SOGS), the Iowa Gambling Task (IGT), the General Decision-Making Style (GDMS), the Gambling Craving Scale (GACS), and a computerized task to measure chasing behavior.
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