AI Article Synopsis
- H-magnetic resonance spectroscopy (H-MRS) is a non-invasive method for studying tissue metabolism, but its application in spinal cord examinations has been limited due to technical challenges.
- A H-MRS protocol was established with healthy volunteers, resulting in the acquisition of 48 spectra from different regions of the spinal cord, revealing the difficulty of working with smaller voxel sizes compared to brain exams.
- About 60% of the spectra obtained were of acceptable quality, suggesting that despite challenges, H-MRS can enhance diagnostic information for intramedullary lesions in the spinal cord.
Article Abstract
Purpose: H-magnetic resonance spectroscopy (H-MRS) is a non-invasive technique that provides information on tissue metabolism and biochemistry. Because of technical difficulties, this method is rarely used in spinal cord examination. The main goal of this study was to develop a routine protocol for MRS of intramedullary lesions.
Material And Methods: A H-MRS protocol was set on a group of healthy volunteers. Forty-eight spectra were acquired in total. Thirty of them were acquired in cervical spinal cord, and the remaining 18 spectra were acquired in the thoracic spinal cord.
Results: In H-MRS of the spinal cord one of the most important problems is small voxel size. Mean voxel size in this study was 7 × 9 × 29 mm, which is much smaller than in brain examinations. Finally, almost 60% of spectra were of acceptable quality in volunteer examinations, which enabled the subsequent examinations.
Conclusions: Challenges of spinal cord spectroscopy were discussed, and the ability of providing additional diagnostic information was proven.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373865 | PMC |
| http://dx.doi.org/10.5114/pjr.2022.118194 | DOI Listing |
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