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Delayed Management of Insulin-Dependent Diabetes Mellitus in Children. | LitMetric

Delayed Management of Insulin-Dependent Diabetes Mellitus in Children.

J Pediatr Health Care

Yu-Chi Annie Wang, Attending Physician, Division of Endocrinology and Diabetes, Arkansas Children's Hospital, and Associate Professor, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR.

Published: December 2022

AI Article Synopsis

  • Diabetic ketoacidosis (DKA) is frequently seen in children with new-onset insulin-dependent diabetes mellitus (IDDM), and delayed diagnosis poses a major risk.
  • Two pediatric endocrinologists reviewed patient records and found that 18% of kids with new-onset IDDM had a delayed diagnosis, with many misdiagnosed or improperly managed.
  • A notable portion (46%) of those with delayed diagnoses ended up presenting with DKA, highlighting the need for better training among healthcare providers to improve early detection and management of IDDM.

Article Abstract

Introduction: Diabetic ketoacidosis (DKA) is a common presentation for pediatric new-onset insulin-dependent diabetes mellitus (IDDM). Delayed diagnosis is the major risk factor for DKA at disease onset.

Method: Two pediatric endocrinologists independently reviewed the admission records to assess the appropriateness of preadmission management in various health care settings.

Results: Eighteen percent (n = 45) of patients with new-onset IDDM had a delayed diagnosis. Twenty-eight were misdiagnosed (respiratory [n = 9], nonspecific [n = 7], genitourinary [n = 4], gastrointestinal [n = 8] issues) and 17 were mismanaged. One child died within 4 hr of hospitalization, presumably because of a hyperosmolar coma. Forty-six percent (n = 21) of patients with delayed diagnosis presented with DKA, comprising 18% of all DKA cases.

Discussion: A significant number of patients with new-onset IDDM were either misdiagnosed or mismanaged. All providers must be appropriately trained in diagnosing new-onset IDDM and follow the standard of clinical care practices.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771990PMC
http://dx.doi.org/10.1016/j.pedhc.2022.07.004DOI Listing

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