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Case reports of Strongyloides stercoralis infection in three patients with haematological malignancies.
Trop Biomed
December 2024
Department of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.
Strongyloidiasis is a parasitic nematode infection mainly caused by Strongyloides stercoralis. Immunocompromised conditions, particularly cancer patients treated with chemotherapy and corticosteroids, have a significant risk of developing Strongyloides hyperinfection. The lack of a gold standard laboratory method to rule out this infection and the insensitivity of microscopic stool examination due to low and intermittent larvae output in stool contribute to the low detection rate of this infection.
View Article and Find Full Text PDFQuantification of ivermectin in veterinary products consumed off-label as a treatment for COVID-19.
Pharmazie
December 2024
Centre of Excellence for Pharmaceutical Sciences (Pharmacen™), North-West University, Potchefstroom, Republic of South Africa.
The COVID-19 pandemic caused global pandemonium, and due to an unprecedented global response, the popularity and use of (veterinary) ivermectin, amongst many other conceivable 'treatments', experienced a meteoric rise. Ivermectin is a macrocyclic lactone compound belonging to the avermectin drug class and is a registered medicine in many countries, although the most common use is as veterinary medicine. In this study, a fast HPLC method was developed and validated for the quantification of ivermectin in veterinary products that were used off-label by a substantial number of people during COVID-19.
View Article and Find Full Text PDFDistribution of ivermectin residues in different Zebu cattle tissues and its stability in thermally processed canned meat.
J Food Sci Technol
January 2025
Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga, SP 13635-900 Brazil.
Ivermectin (IVM) is one of the most widely used antiparasitic drugs worldwide and has become the drug of choice for anthelmintic and tick treatment in beef cattle production. Drugs used in production animals requires a withdrawal period after treatment to avoid residual concentrations above the defined maximun residue level (MRL). The aims of this study were to quantify the residue level of IVM in different muscles of cattle at several different time periods following 1% or 3.
View Article and Find Full Text PDFA combined treatment regimen for infection in in southern China.
Int J Parasitol Parasites Wildl
April 2025
State Key Laboratory for Animal Disease Control and Prevention, Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong, 510642, China.
The Sichuan snub-nosed monkey () is an endangered species in China and is susceptible to infection with species. However, the worms are difficult to remove completely. A practical treatment regimen for trichuriasis was conducted over a seven-month period on 15 in a wildlife zoo in southern China.
View Article and Find Full Text PDFFirst morphological and molecular characterisation of Spirometra mansoni (Cestoda, Diphyllobothriidae) in a domestic cat from Veracruz, Mexico.
Vet Parasitol Reg Stud Reports
January 2025
Laboratory of Helminthology, Faculty of Microbiology, University of Costa Rica, San José, Costa Rica.
Cestodes of the genus Spirometra are multi-host parasites that are the causative agents of spirometrosis in domestic and wild carnivores and sparganosis in humans, endemic diseases in tropical and subtropical regions. In domestic animals, the infection is usually asymptomatic or produces gastrointestinal signs such as vomiting and chronic diarrhoea. In humans, an incidental parasitosis develops where the plerocercoid can lodge in tissues and cause a variety of symptoms, including neuropathies, blindness, paralysis, and death.
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