Background: Trigeminal neuralgia is considered the worst pain a human being can experience. Initial treatment uses anticonvulsant sodium channel blockers, which relieve pain in approximately 70% of patients. In refractory cases, it is possible to perform ablative treatments, decompressive surgeries, and neuromodulatory techniques.
Methods: This report describes the treatment of a patient with refractory trigeminal neuralgia who continued to have a painful clinical presentation after four surgical procedures and three ablative procedures. The patient presented with severe pain (verbal numerical scale between 9 and 10), manifesting an evident suicidal ideation. A dorsal root ganglion (DRG) stimulation electrode was implanted in the trigeminal ganglion through intraoral puncture with maxillary fixation of the electrode, in order to minimize the chances of displacement. The test phase consisted of implanting a quadripolar electrode for DRG stimulation through puncture lateral to the buccal rim in a fluoroscopic coaxial view. The electrode was fixed to the skin and maintained for 5 days, during which the patient remained completely pain free. After the 5-day test period, the definitive stimulation electrode was implanted, this time with intraoral puncture and maxillary electrode fixation.
Results: The patient remains pain free in the 3-month follow-up, with no displacement of the electrode.
Conclusions: The DRG electrode may be considered a therapeutic option in patients with severe trigeminal neuralgia. Controlled studies must be performed to determine the efficacy and safety of the method.
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http://dx.doi.org/10.1093/pm/pnac120 | DOI Listing |
Exp Brain Res
January 2025
Department of Rehabilitation Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 510080, China.
Vestibular dysfunction has been reported as a potential cause in adolescent idiopathic scoliosis (AIS). However, it remained unclear how stochastic galvanic vestibular stimulation (GVS) affected kinetic performance of patients with AIS. This study aimed to investigate the effect of stochastic GVS on ground reaction forces (GRF) measures during obstacle negotiation among patients with AIS.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
January 2025
Department of Audiovestibology, ASST dei Sette Laghi, Via Lazio, 21100, Varese, VA, Italy.
Purpose: Evaluate the feasibility and safety of a robotic electrode insertion in pediatric cochlear implantation and compare the results with manually inserted electrodes in the same subject.
Methods: Retrospective case series review of four children who underwent bilateral cochlear implantation with the same array: on one side, the array was inserted using the robot, while on the other side the array was inserted manually. Behavioural and electrophysiological measures were compared.
Colloids Surf B Biointerfaces
January 2025
State Key Laboratory of Precision Manufacturing for Extreme Service Performance, College of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China; Jiangxi Province Key Laboratory of Additive Manufacturing of Implantable Medical Device, Jiangxi University of Science and Technology, Nanchang 330013, China. Electronic address:
Electrical stimulation displayed tremendous potential in promoting nerve regeneration. However, the current electrical stimulation therapy required complex traversing wires and external power sources, which significantly limited its practical application. Herein, a self-powered nerve scaffold based on primary battery principle was gradient printed by laser additive manufacturing technique.
View Article and Find Full Text PDFJ Neural Eng
January 2025
School of Physics and Astronomy, Cardiff University, The Parade, Cardiff, CF10 3XQ, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Objective: Inclusion of individualised electrical conductivities of head tissues is crucial for the accuracy of electrical source imaging techniques based on electro/magnetoencephalography and the efficacy of transcranial electrical stimulation. Parametric electrical impedance tomography (pEIT) is a method to cheaply and non-invasively estimate them using electrode arrays on the scalp to apply currents and measure the resulting potential distribution. Conductivities are then estimated by iteratively fitting a forward model to the measurements, incurring a prohibitive computational cost that is generally lowered at the expense of accuracy.
View Article and Find Full Text PDFTrends Hear
January 2025
Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
When listening to speech under adverse conditions, listeners compensate using neurocognitive resources. A clinically relevant form of adverse listening is listening through a cochlear implant (CI), which provides a spectrally degraded signal. CI listening is often simulated through noise-vocoding.
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