A paradigm shift in the physics of laser-plasma interactions is approaching with the commissioning of multipetawatt laser facilities worldwide. Radiation reaction processes will result in the onset of electron-positron pair cascades and, with that, the absorption and partitioning of the incident laser energy, as well as the energy transport throughout the irradiated targets. To accurately quantify these effects, one must know the focused intensity on target in situ. In this work, a way of measuring the focused intensity on target is proposed based upon the ionization of xenon gas at low ambient pressure. The field ionization rates from two works [Phys. Rev. A 59, 569 (1999)1050-294710.1103/PhysRevA.59.569 and Phys. Rev. A 98, 043407 (2018)2469-992610.1103/PhysRevA.98.043407], where the latter rate has been derived using quantum mechanics, have been implemented in the particle-in-cell code SMILEI [Comput. Phys. Commun. 222, 351 (2018)0010-465510.1016/j.cpc.2017.09.024]. A series of one- and two-dimensional simulations are compared and shown to reproduce the charge states without presenting visible differences when increasing the simulation dimensionality. They provide a way to accurately verify the intensity on target using in situ measurements.
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http://dx.doi.org/10.1103/PhysRevE.106.015205 | DOI Listing |
Arch Cardiovasc Dis
December 2024
Department of Cardiology, CHU Montpellier, 34295 Montpellier, France.
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View Article and Find Full Text PDFBMJ Open
December 2024
School of Health & Wellbeing, University of Glasgow, Glasgow, UK.
Introduction: Fear of recurrence is a transdiagnostic problem experienced by people with psychosis, which is associated with anxiety, depression and risk of future relapse events. Despite this, there is a lack of available psychological interventions for fear of recurrence, and psychological therapies for schizophrenia are often poorly implemented in general. However, low-intensity psychological therapy is available for people who experience fear of recurrence in the context of cancer, which means there is an opportunity to learn what has worked in a well-implemented psychological therapy to see if any learning can be adapted for schizophrenia care.
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December 2024
Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul, 08826, Republic of Korea; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address:
At-risk conifer stands growing in hot, arid conditions at low elevations may contain the most climate change-adapted seeds needed for sustainable forestry. This study used a triage framework to identify high-priority survey areas for Pinus ponderosa (Pipo) within a large region, by intersecting an updated range map with a map of seed zones and elevation bands (SZEBs). The framework assesses place-based climate change and potential wildfire risks by rank-order across 740 potential collection units.
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TCM Gynecology Department, Hangzhou Hospital of Traditional Chinese Medicine, NO.453 Ti Yuchang Road, Hangzhou, 310007, Zhejiang, China.
Objective: He Shi Yu Lin Formula (HSYLF) is a clinically proven prescription for treating premature ovarian insufficiency (POI), and has shown a good curative effect. However, its molecular mechanisms are unclear. This study aimed to investigate the molecular mechanisms of HSYLF and clarify how network pharmacology analysis guides the design of animal experiments, including the selection of effective treatment doses and key targets, to ensure the relevance of the experimental results.
View Article and Find Full Text PDFSci Rep
December 2024
BioMag Laboratory, HUS Diagnostic Center, Helsinki University Hospital, University of Helsinki and Aalto University School of Science, Helsinki, Finland.
A novel variant of paired-associative stimulation (PAS) consisting of high-frequency peripheral nerve stimulation (PNS) and high-intensity transcranial magnetic stimulation (TMS) above the motor cortex, called high-PAS, can lead to improved motor function in patients with incomplete spinal cord injury. In PAS, the interstimulus interval (ISI) between the PNS and TMS pulses plays a significant role in the location of the intended effect of the induced plastic changes. While conventional PAS protocols (single TMS pulse often applied with intensity close to resting motor threshold, and single PNS pulse) usually require precisely defined ISIs, high-PAS can induce plasticity at a wide range of ISIs and also in spite of small ISI errors, which is helpful in clinical settings where precise ISI determination can be challenging.
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