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http://dx.doi.org/10.14309/ajg.0000000000001892 | DOI Listing |
Surg Neurol Int
December 2024
Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Background: Propofol is one of the most used intravenous anesthetic agents in traumatic brain injury (TBI) patients undergoing emergency neurosurgical procedures. Despite being efficacious, its administration is associated with dose-related adverse effects. The use of adjuvants along with propofol aids in limiting its consumption, thereby mitigating the side effects related to propofol usage.
View Article and Find Full Text PDFHellenic J Cardiol
December 2024
Division of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan. Electronic address:
Background: Epicardial stenosis and coronary microvascular dysfunction (CMD) may coexist in patients with chronic coronary syndrome (CCS). Microvascular resistance reserve (MRR) has been demonstrated to be a valid cross-modality metric using continuous saline infusion thermodilution and intracoronary Doppler flow velocity methods. This study aimed to investigate the prevalence and diagnostic concordance of CMD defined by MRR using two methods-stress transthoracic Doppler echocardiography (S-TDE) and the invasive bolus thermodilution method (B-Thermo)-in patients with functionally significant epicardial stenosis.
View Article and Find Full Text PDFAm J Physiol Heart Circ Physiol
January 2025
Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, United States.
Insulin has important vasodilatory effects in the peripheral circulation, but less is known about insulin's role in cerebrovascular control. Herein, we hypothesized both systemic (intravenous) and local (intranasal) insulin administration would increase indices of cerebral blood flow and reduce cerebrovascular compliance (Ci) in young adults. Participants were assigned to one of four separate protocols.
View Article and Find Full Text PDFJ Anaesthesiol Clin Pharmacol
August 2023
Department of Anesthesiology and Critical Care, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Target-controlled infusion (TCI) is a novel drug delivery system wherein a microprocessor calculates the rate of drug to be infused based upon the target plasma or effect site concentration set by the operator. It has found its place in the operation theaters and intensive care units (ICUs) for safe administration of intravenous anesthesia and analgosedation using drugs like propofol, dexmedetomidine, opioids, and so on. Operating a TCI device requires the user to have a primitive understanding of drug pharmacokinetics and pharmacodynamics and an awareness of the practical problems that can arise during its administration.
View Article and Find Full Text PDFIntegr Comp Biol
October 2024
Black in Marine Science, Chief Executive Officer, Alpharette, Georgia 30004, USA.
At Black in Marine Science (BIMS), the integration of joy-centered leadership principles has emerged as a transformative blueprint for empowering leaders and fostering inclusive environments. This article explores the integration of the Formula for Joy (F4J) model within BIMS, providing a comprehensive overview of its principles and practices. It presents the model as an adaptable leadership approach suitable for a diverse range of leaders and organizational contexts.
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