Studying the Association Between Occupational Stress and Urinary Levels of Oxidative Stress Biomarkers (8-OHdG and Biopyrrins) in Brickfield Workers.

J Occup Environ Med

From the Occupational and Environmental Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Published: January 2023

AI Article Synopsis

  • The study aimed to measure occupational stress (OS) levels among brickfield workers and examine its relationship with oxidative stress.
  • Eighty-six brickfield workers and 90 administrative controls were assessed using the Occupational Stress Index, and oxidative biomarkers were measured in their urine.
  • Results showed that brickfield workers experienced higher OS and oxidative biomarker levels, and there was a significant correlation between these factors, indicating a strong association between occupational and oxidative stress.

Article Abstract

Objectives: The aims of the study are to measure the prevalence and level of occupational stress (OS) and to explore its association with oxidative stress among some brickfield workers.

Methods: Eighty-six brickfield workers and 90 administrative controls were assessed using the Arabic validated version of the Occupational Stress Index. The urinary levels of oxidative biomarkers; 8-hydroxy-2'-deoxyguanosine and biopyrrins were also measured.

Results: The prevalence of moderate and severe OS in addition to the urinary levels of both oxidative biomarkers was significantly higher among the brickfield workers compared with their controls. Both biomarkers levels were significantly and positively correlated with scores of Occupational Stress Index, duration of employment, and with each other. The receiver operating characteristic analysis showed significant specificity and sensitivity of both biomarkers for determining the level of OS.

Conclusions: A significant association between occupational and oxidative stresses was detected in brickfield workers.

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Source
http://dx.doi.org/10.1097/JOM.0000000000002677DOI Listing

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