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Differential Diagnosis of a Canalicular Adenoma: A Case Report and Literature Review.
Cureus
January 2025
Department of Oral and Maxillofacial Surgery, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, GBR.
We report the case of a 68-year-old female patient who was referred to our hospital for a painless, immobile, hard and well-circumscribed nodule of the upper lip that had been present for a decade. Surgical excision under local anaesthesia was the treatment of choice. After histological examination, a diagnosis of a canalicular adenoma, an uncommon benign salivary gland tumour, was made.
View Article and Find Full Text PDFCheilitis granulomatosa, a rare condition in children, is marked by painless, sudden lip swelling, which can last for an extended period. Since cheilitis granulomatosa can precede gastrointestinal symptoms in some cases of Crohn's disease, a comprehensive evaluation before administering systemic inflammatory modulatory treatments and long-term follow-up is necessary.
View Article and Find Full Text PDFA curious case of a solitary lower lip papule: A case report.
Indian J Pathol Microbiol
February 2025
Department of Pathology, IPGME and R, Kolkata, West Bengal, India.
Solitary small painless lower lip lesions are common and can be of variable etiologies, giving rise to a wide number of clinical and histopathological differentials. From a clinico-pathological perspective, the diagnostic differentials may vary from vascular malformation, basal cell carcinoma, epidermal cyst, traumatic neuroma, neurofibroma, schwannoma, neurilemmoma, skin adnexal tumor, to other mucosal neuromas. Here we are reporting one such rare case masquerading as mucocele in a patient aged 37 years who reported first time at the ENT outpatient department.
View Article and Find Full Text PDFChondroitin sulfate-based dissolvable microneedles loaded with NIR-II photothermal and natural anticancer agents for synergistic melanoma therapy.
Int J Biol Macromol
April 2025
School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China. Electronic address:
Melanoma is characterized by its aggressiveness, high metastatic potential, and numerous mutations, which limit the effectiveness of current treatments. To address this issue, we developed a dissolvable microneedle (MN) system composed of poly(2-ethyl-2-oxazoline) (PEtOz) and chondroitin sulfate (CS). This MN system was loaded with liposomes containing both a NIR-II photothermal small molecule (IRLy) and the natural anticancer agent Gambogic acid (GA), forming Lip(IRLy + GA) MNs.
View Article and Find Full Text PDFPulse oximetry at two sensor placement sites in conscious foals.
Acta Vet Scand
January 2025
Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Viikintie 49, 00014, Helsinki, Finland.
Background: Pulse oximetry has not been thoroughly evaluated for assessment of oxygenation in conscious foals. Compared with invasive arterial blood sampling, it is a painless and non-invasive method for real-time monitoring of blood oxygen saturation. The aim of this prospective clinical study was to evaluate the usability, validity, and reliability of pulse oximetry at two measuring sites (lip and caudal abdominal skin fold) for blood oxygen saturation measurement in conscious foals with and without respiratory compromise.
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