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Interaction between bacterial adhesins leads to coaggregation by the oral bacteria and .
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Antimicrobial Resistance, Omics and Microbiota Group, Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, United Kingdom.
is an unusual diderm firmicute that plays a central role in the formation of dental biofilm formation through coaggregation with many other oral bacteria. However, the molecular interactions leading to oral biofilm formation are largely unknown. In a recent study (L.
View Article and Find Full Text PDFPsychiatric poetics: mental healthcare and Giovanni Stanghellini's 'Logics of Discovery'.
BJPsych Bull
January 2025
University of Manchester, Manchester, UK.
The importance of art and humanities in mental health is widely recognised, and consumption and creation of poetry, prose, drama and the plastic arts are now considered to be relevant knowledge-generating and therapeutic activities. However, literary and art criticism remain at the margins. By contrast, in his two 'Logics of Discovery' papers, psychiatrist, psychopathologist and psychotherapist Giovanni Stanghellini brings to bear on clinical discovery and the healing alliance cultural historian Aby Warburg's approach to images (specifically, his ) and philosopher Giorgio Agamben's analysis of the linguistic phenomenon of parataxis in Friedrich Hölderlin's poetry.
View Article and Find Full Text PDFEditorial Comment on "Optimizing Care for Women through Gynecologic Organ Considerations During Cystectomy: A Pre-Operative Checklist of Important Considerations".
Urology
January 2025
Columbia University Irving Medical Center, Department of Urology. Electronic address:
Predatory journals: what can we do to protect their prey?
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La Tunisie Médicale, Tunis, Tunisia.
Brain aging and rejuvenation at single-cell resolution.
Neuron
January 2025
Department of Genetics, Stanford University, Stanford, CA, USA; Glenn Center for the Biology of Aging, Stanford University, Stanford, CA, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA. Electronic address:
Brain aging leads to a decline in cognitive function and a concomitant increase in the susceptibility to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. A key question is how changes within individual cells of the brain give rise to age-related dysfunction. Developments in single-cell "omics" technologies, such as single-cell transcriptomics, have facilitated high-dimensional profiling of individual cells.
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