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Reduce electrical overload via threaded Chinese acupuncture in nerve electrical therapy.
Bioact Mater
April 2025
Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
Bioelectrical stimulation is a powerful technique used to promote tissue regeneration, but it can be hindered by an "electrical overload" phenomenon in the core region of stimulation. We develop a threaded microneedle electrode system that protects against "electrical overload" by delivering medicinal hydrogel microspheres into the core regions. The threaded needle body is coated with polydopamine and chitosan to enhance the adhesion of microspheres, which are loaded into the threaded grooves, allowing for their stereoscopic release in the core regions.
View Article and Find Full Text PDFAssociation between phase angle and daily creatinine excretion changes in critically ill patients: an approach to muscle mass.
Front Physiol
January 2025
Departamento de Paciente Crítico, Clínica Alemana de Santiago, Santiago, Chile.
Assessing muscle mass in critically ill patients remains challenging. This retrospective cohort study explores the potential of phase angle (PA°) derived from bioelectrical impedance analysis (BIA) as a surrogate marker for muscle mass monitoring by associating it with daily creatinine excretion (DCE), a structural and metabolic muscle mass marker. In 20 ICU patients, we observed a linear relationship between PA° and DCE at initial (S1) and follow-up (S2) points, with Rho values of 0.
View Article and Find Full Text PDFPrevalence of and risk factors for sarcopenia in patients with epilepsy.
Seizure
January 2025
Department of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Background: Epilepsy is a chronic neurological disorder with a burden of comorbidities. Knowledge regarding sarcopenia prevalence and associated risk factors in patients with epilepsy remains limited, which prompted us to conduct the present study.
Methods: This cross-sectional study enrolled patients with epilepsy from our epilepsy clinic and controls from the staff at National Cheng Kung University Hospital, Tainan, Taiwan.
Interaction of genetics risk score and fatty acids quality indices on healthy and unhealthy obesity phenotype.
BMC Med Genomics
January 2025
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Background: The growth in obesity and rates of abdominal obesity in developing countries is due to the dietary transition, meaning a shift from traditional, fiber-rich diets to Westernized diets high in processed foods, sugars, and unhealthy fats. Environmental changes, such as improving the quality of dietary fat consumed, may be useful in preventing or mitigating the obesity or unhealthy obesity phenotype in individuals with a genetic predisposition, although this has not yet been confirmed. Therefore, in this study, we investigated how dietary fat quality indices with metabolically healthy obesity (MHO) or metabolically unhealthy obesity (MUO) based on the Karelis criterion interact with genetic susceptibility in Iranian female adults.
View Article and Find Full Text PDFApplication of bioelectrical impedance detection techniques: Cells and tissues.
Biosens Bioelectron
January 2025
College of Mathematical Medicine, Zhejiang Normal University, Jinhua, China; Affiliated Dongyang Hospital of Wenzhou Medical University, Jinhua, China. Electronic address:
Pathological conditions in organisms often arise from various cellular or tissue abnormalities, including dysregulation of cell numbers, infections, aberrant differentiation, and tissue pathologies such as lung tumors and skin tumors. Thus, developing methods for analyzing and identifying these biological abnormalities presents a significant challenge. While traditional bioanalytical methods such as flow cytometry and magnetic resonance imaging are well-established, they suffer from inefficiencies, high costs, complexity, and potential hazards.
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