Chiral allenylcarbonyls such as allenoates remain underutilized in complex synthesis despite recent advances in synthesis methods to prepare them non-racemically. The field is now ripe for the employment of this class of allenes as building blocks to facilitate the construction of complex small-molecule compounds, such as bridged bicycles.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365116 | PMC |
http://dx.doi.org/10.2174/1570178619666211231113033 | DOI Listing |
Lett Org Chem
August 2022
Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida 33431, USA.
Chiral allenylcarbonyls such as allenoates remain underutilized in complex synthesis despite recent advances in synthesis methods to prepare them non-racemically. The field is now ripe for the employment of this class of allenes as building blocks to facilitate the construction of complex small-molecule compounds, such as bridged bicycles.
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