This study aims to determine the level of nine trace elements - As, Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn in liver, gill and muscle of in Bukit Merah Lake (BML). The concentration of trace elements was measured using Inductively Coupled Plasma-Optical Emission Spectrometers (ICP-OES). Cd and Ni were found below the detection level, while Cr was only detected in gill and muscle tissues. The Metal Pollution Index (MPI) established were liver > gill > muscle. The ranking order of trace elements in the gills was Fe > Zn > Mn > Pb > As > Cu > Cr. For the liver, the ranking order was Fe > Cu > Zn > As > Mn > Pb, while in the muscle, the ranking order was Fe > Zn > Pb > As > Cu > Mn > Cr. The estimated daily intake (EDI) for all the trace elements in this study was calculated based on 168 g.day of Malaysians' fish consumption, indicating no potential risk. From the human health point of view, there was no significant non-carcinogenic risk of individual trace elements as evaluated by Target Hazard Quotient (THQ). As indicated by the Hazardous Index (HI), the cumulative effect of all trace elements also suggested no potential of non-carcinogenic risk. The carcinogenic risks assessed from Pb and As were also neglectable and there was no likelihood of getting cancer during one's life span.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354902 | PMC |
| http://dx.doi.org/10.21315/tlsr2022.33.2.9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Nanoparticle-Mediated Cuproptosis and Photodynamic Synergistic Strategy: A Novel Horizon for Cancer Therapy.
Cancer Med
February 2025
Department of General Surgery, The First People's Hospital of Baiyin (Third Affiliated Hospital of Gansu University of Traditional Chinese Medicine), Baiyin, China.
Background: Photodynamic therapy (PDT) is a noninvasive cancer treatment that works by using light to stimulate the production of excessive cytotoxic reactive oxygen species (ROS), which effectively eliminates tumor cells. However, the therapeutic effects of PDT are often limited by tumor hypoxia, which prevents effective tumor cell elimination. The oxygen (O) consumption during PDT can further exacerbate hypoxia, leading to post-treatment adverse events.
View Article and Find Full Text PDFBackground: Childhood obesity and the rate of its spread is a serious threat to the reproductive health of the nation, especially among boys, being a background for delaying sexual development and further disrupting fertility.
Aim: To study the peculiarities of the ratio of the level of leptin and a number of toxic and essential chemical trace elements in biological environments in adolescent boys aged 13-14 years with obesity and delayed sexual development.
Materials And Methods: Three groups of adolescents aged 13-14 years were studied and formed: the main ones - with constitutional exogenous obesity of 1-2 degrees (1-20 boys without secondary signs of puberty; 2 - 24 boys with 2-4 stages of puberty according to Tanner) and comparisons (3 - 15 boys with normal body weight and without deviations in puberty).
Backgrounds And Aims: Type 2 diabetes and its complications are assumed to be major public health problems globally. Zinc is one of the elements that play a part in insulin secretion and signaling. Therefore, this study seeks the answer to the following question: "What are the effects of 220 mg zinc sulfate supplementation on the weight, blood pressure, and glycemic control of patients with Type 2 diabetes?".
View Article and Find Full Text PDFKetogenic diet with oxyresveratrol and zinc inhibits glioblastoma and restores memory function and motor coordination.
Oncol Res
January 2025
Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, India.
Background: To date, there is no effective cure for the highly malignant brain tumor glioblastoma (GBM). GBM is the most common, aggressive central nervous system tumor (CNS). It commonly originates in glial cells such as microglia, oligodendroglia, astrocytes, or subpopulations of cancer stem cells (CSCs).
View Article and Find Full Text PDFNutritional and functional outcomes in trials of nutrient-stimulated hormone-based therapy-A systematic mapping review.
Obes Rev
January 2025
Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Nutrition, Centre Spécialisé Obésité, Hôpital Européen Georges Pompidou, Paris, France.
Introduction: Currently, trials are investigating the efficacy of nutrient-stimulated hormone-based therapies (NuSHs) in promoting weight loss in people living with overweight and obesity. However, the extent to which nutritional and functional outcomes are evaluated remains uncertain. Thus, we conducted a systematic mapping to assess the presence of nutritional and functional outcomes in randomized controlled trials (RCTs) investigating NuSHs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!