AI Article Synopsis
- Research shows that menstrual blood loss significantly contributes to iron deficiency in premenopausal women, influenced by hormones like estrogen and progesterone during the menstrual cycle.
- Despite the prevalence of this issue, there is a lack of targeted research on female-specific causes and treatments for iron deficiency.
- The review discusses factors affecting iron status in active premenopausal females, provides practical guidelines for management, and suggests areas for future research to improve understanding of iron metabolism in this group.
Article Abstract
Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and contribute to variations in iron parameters throughout the menstrual cycle. Despite the high prevalence of iron deficiency in premenopausal females, scant research has investigated female-specific causes and treatments for iron deficiency. In this review, we provide a comprehensive discussion of factors that influence iron status in active premenopausal females, with a focus on the menstrual cycle. We also outline several practical guidelines for monitoring, diagnosing, and treating iron deficiency in premenopausal females. Finally, we highlight several areas for further research to enhance the understanding of iron metabolism in this at-risk population.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366739 | PMC |
| http://dx.doi.org/10.3389/fspor.2022.903937 | DOI Listing |
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