This report briefly describes several cases of diverticula simulating colonic mucosal lesions. We have found that the bowler hat configuration, in particular, frequently occurs in the presence of diverticular disease. In our series, no polyp was found to exhibit the bowler hat sign, while 12 cases of diverticular disease displayed 1 or more "bowler hats." Differentiation between polyps and diverticula displaying the bowler hat sign may be possible, but we conclude that the bowler hat sign per se is a nonspecific finding and that additional views may be necessary to confirm the presence of polyps.
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Sci Adv
June 2023
Hobby-Eberly Telescope, The University of Texas at Austin, Austin, TX 78712, USA.
Capturing planets in the act of losing their atmospheres provides rare opportunities to probe their evolution history. This analysis has been enabled by observations of the helium triplet at 10,833 angstrom, but past studies have focused on the narrow time window right around the planet's optical transit. We monitored the hot Jupiter HAT-P-32 b using high-resolution spectroscopy from the Hobby-Eberly Telescope covering the planet's full orbit.
View Article and Find Full Text PDFAbdom Radiol (NY)
May 2018
Department of Radiology, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, Hong Kong SAR.
Am J Physiol Lung Cell Mol Physiol
July 2016
Department of Radiation Oncology, University of Iowa, Iowa City, Iowa.
Epigenetic mechanisms, including DNA methylation and histone acetylation, regulate gene expression in idiopathic pulmonary arterial hypertension (IPAH). These mechanisms can modulate expression of extracellular superoxide dismutase (SOD3 or EC-SOD), a key vascular antioxidant enzyme, and loss of vascular SOD3 worsens outcomes in animal models of pulmonary arterial hypertension. We hypothesized that SOD3 gene expression is decreased in patients with IPAH due to aberrant DNA methylation and/or histone deacetylation.
View Article and Find Full Text PDFNucleic Acids Res
September 2011
Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Centre National de la Recherche Scientifique (CNRS) UMR8197 - Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, 46 rue d'Ulm, 75230 Paris cedex 05, France.
Transposable elements (TEs) and their relics play major roles in genome evolution. However, mobilization of TEs is usually deleterious and strongly repressed. In plants and mammals, this repression is typically associated with DNA methylation, but the relationship between this epigenetic mark and TE sequences has not been investigated systematically.
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