AI Article Synopsis
Article Abstract
Purpose: The primary aim of this study was to evaluate the 3-dimensional morphology of the proximal tibia around the osteotomy plane in open-wedge high tibial osteotomy, focusing on the posterolateral (PL) and posteromedial (PM) tibial condyles, and to clarify the changes in morphologic parameters due to differences in patient characteristics and hinge position. The secondary aim was to examine whether morphologic features were associated with insufficient osteotomy, which increases the risk of lateral hinge fracture (LHF).
Methods: The PL and PM anteroposterior distance, asymmetry ratio, and discrepancy between PL and PM distances along the tibial osteotomy plane were measured. We investigated changes in the parameters due to differences in patient characteristics and hinge position. Osteotomy configurations and LHFs were evaluated using postoperative computed tomography scans.
Results: The 3-dimensional preoperative plans of 117 knees (male, 41 knees; female, 76 knees) were evaluated. PL distances were larger than PM distances in almost all cases. The average asymmetry ratio was 1.35, and the standard deviation was 0.22. Higher hinge position was associated with a larger asymmetry ratio and discrepancy (P < .001). The asymmetry ratio and discrepancy were independently positively correlated with male sex (P = .002 and P = .001, respectively) and gentle posterior tibial slope (P < .001 and P < .001, respectively). Osteotomies with type III LHFs showed lower osteotomy sufficiency than osteotomies without LHFs (P < .001).
Conclusions: PL tibial condyle protrusion was more pronounced in male patients and those with a high hinge position, and may result in insufficient PL osteotomy, which is a risk factor for type III LHF during open-wedge high tibial osteotomy. The optimal hinge position was located approximately 15 mm and 20 mm distal to the lateral tibial plateau in female and male patients, respectively.
Level Of Evidence: IV: retrospective case series.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.arthro.2022.07.018 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hinged Carboxylate in the Artificial Distal Pocket of an Iron Porphyrin Enhances CO Electroreduction at Low Overpotential.
Adv Sci (Weinh)
January 2025
Université Paris-Saclay, CNRS, Institut de Chimie Moléculaire et des Matériaux d'Orsay, Orsay, 91400, France.
To efficiently capture, activate, and transform small molecules, metalloenzymes have evolved to integrate a well-organized pocket around the active metal center. Within this cavity, second coordination sphere functionalities are precisely positioned to optimize the rate, selectivity, and energy cost of catalytic reactions. Inspired by this strategy, an artificial distal pocket defined by a preorganized 3D strap is introduced on an iron-porphyrin catalyst (sc-Fe) for the CO-to-CO electrocatalytic reduction.
View Article and Find Full Text PDFHinge Position Dominance Over Osteotomy Inclination in Medial Open-Wedge High Tibial Osteotomy: A Key Factor in Posterior Tibial Slope Changes.
Cartilage
January 2025
Department of Biomedical Engineering, University of Twente, Enschede, The Netherlands.
Objective: A medial open-wedge high tibial osteotomy (MOWHTO) may increase the posterior tibial slope (PTS). The purpose of this study was to determine the effect of the osteotomy inclination angle (in the sagittal plane) in combination with different hinge positions (in the transverse plane) on the change in PTS due to a MOWHTO.
Methods: We developed a mathematical approach to determine the effect of the osteotomy inclination angle combined with different hinge positions.
Floodplain forests drive fruit-eating fish diversity at the Amazon Basin-scale.
Proc Natl Acad Sci U S A
January 2025
Centre de Recherche sur la Biodiversité et l'Environnement, Université de Toulouse, Institut de Recherche pour le Développement, Institut National Polytechnique de Toulouse, Université Toulouse 3 - Paul Sabatier, Toulouse F-31062, France.
Unlike most rivers globally, nearly all lowland Amazonian rivers have unregulated flow, supporting seasonally flooded floodplain forests. Floodplain forests harbor a unique tree species assemblage adapted to flooding and specialized fauna, including fruit-eating fish that migrate seasonally into floodplains, favoring expansive floodplain areas. Frugivorous fish are forest-dependent fauna critical to forest regeneration via seed dispersal and support commercial and artisanal fisheries.
View Article and Find Full Text PDFVariations in linear energy transfer distributions within a European proton therapy planning comparison of paediatric posterior fossa tumours.
Phys Imaging Radiat Oncol
October 2024
Aarhus University Hospital, Danish Centre for Particle Therapy, Aarhus N, Denmark.
Background And Purpose: Radiotherapy for paediatric posterior fossa tumours may cause complications in the brainstem and upper spinal cord due to high doses. With proton therapy (PT) this risk may increase due to higher relative biological effectiveness (RBE) from elevated linear energy transfer (LET). This study assesses variations in LET in the brainstem and spinal cord in proton treatment plans from European centres.
View Article and Find Full Text PDFElucidating the structure and function of a membrane-active plant protein domain using in silico mutagenesis.
Biochim Biophys Acta Biomembr
January 2025
Land and Food Systems, University of British Columbia, Vancouver, Canada; Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, Edmonton, Canada. Electronic address:
The Solanum tuberosum (common potato) plant specific insert (StPSI) is an antimicrobial protein domain that exhibits membrane-disrupting and membrane-fusing activity upon dimerization at acidic pH, activity proposed to involve electrostatic attraction and membrane anchoring mediated by specific positively-charged and conserved tryptophan residues, respectively. This study is the first to employ an in silico mutagenesis approach to clarify the structure-function relationship of a plant specific insert (PSI), where ten rationally-mutated StPSI variants were investigated using all-atom and coarse-grained molecular dynamics. The tryptophan (W) residue at position 18 (W18) of wild-type StPSI was predicted to confer structural flexibility to the dimer and mediate a partial separation of the assembled monomers upon bilayer contact, while residues including W77 and the lysine (K) residue at position 83 (K83) were predicted to stabilize secondary structure and influence association with the model membrane.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!