Purpose: To provide contemporary and future estimates of childhood myopia prevalence in Africa.
Methods: A systematic online literature search was conducted for articles on childhood (≤18 years) myopia (spherical equivalent [SE] ≤ -0.50D; high myopia: SE ≤ -6.00D) in Africa. Population- or school-based cross-sectional studies published from 1 Jan 2000 to 30 May 2021 were included. Meta-analysis using Freeman-Tukey double arcsine transformation was performed to estimate the prevalence of childhood myopia and high myopia. Myopia prevalence from subgroup analyses for age groups and settings were used as baseline for generating a prediction model using linear regression.
Results: Forty-two studies from 19 (of 54) African countries were included in the meta-analysis (N = 737,859). Overall prevalence of childhood myopia and high myopia were 4.7% (95% CI: 3.3%-6.5%) and 0.6% (95% CI: 0.2%-1.1%), respectively. Estimated prevalence across the African regions was highest in the North (6.8% [95% CI: 4.0%-10.2%]), followed by Southern (6.3% [95% CI: 3.9%-9.1%]), East (4.7% [95% CI: 3.1%-6.7%]) and West (3.5% [95% CI: 1.9%-6.3%]) Africa. Prevalence from 2011 to 2021 was approximately double that from 2000 to 2010 for all studies combined, and between 1.5 and 2.5 times higher for ages 5-11 and 12-18 years, for boys and girls and for urban and rural settings, separately. Childhood myopia prevalence is projected to increase in urban settings and older children to 11.1% and 10.8% by 2030, 14.4% and 14.1% by 2040 and 17.7% and 17.4% by 2050, respectively; marginally higher than projected in the overall population (16.4% by 2050).
Conclusions: Childhood myopia prevalence has approximately doubled since 2010, with a further threefold increase predicted by 2050. Given this trajectory and the specific public health challenges in Africa, it is imperative to implement basic myopia prevention programmes, enhance spectacle coverage and ophthalmic services and generate more data to understand the changing myopia epidemiology to mitigate the expanding risk of the African population.
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http://dx.doi.org/10.1111/opo.13035 | DOI Listing |
Asia Pac J Ophthalmol (Phila)
January 2025
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong; Hong Kong Hub of Paediatric Excellence, The Chinese University of Hong Kong, Hong Kong. Electronic address:
Myopia is associated with interactive effects of genetic and environmental factors. The development of myopia in childhood is likely to be more dependent on genetic background. Candidate gene analysis, whole exome sequencing, genome-wide association studies (GWAS) and subsequent metaanalyses have identified more than 400 loci that are associated with myopia.
View Article and Find Full Text PDFJ Clin Med
December 2024
Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warszawa, Poland.
: As Repeated Low-Level Red Light (RLRL) therapy is becoming increasingly prevalent in clinical practice, mainly in the Far East, largely due to its child-friendly nature and the feasibility of home use, this study aims to conduct a systematic review and meta-analysis to evaluate the efficacy of RLRL therapy in managing childhood myopia, specifically in relation to axial length (AL) and spherical equivalent refraction (SER), across a larger group of children aged from 6 to 16 years. : A systematic literature search was performed using PubMed, Scopus, and Web of Science to access relevant databases and to locate outcome studies. Eligibility criteria included publication type, participant characteristics, and outcomes report.
View Article and Find Full Text PDFHum Genet
January 2025
Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Refractive error (RE) and myopia are complex polygenic conditions with the majority of genome-wide associated genetic variants in non-exonic regions. Given this, and the onset during childhood, gene-regulation is expected to play an important role in its pathogenesis. This prompted us to explore beyond traditional gene finding approaches.
View Article and Find Full Text PDFChildren (Basel)
December 2024
Institute of Epidemiology and Healthcare, Faculty of Population Health Sciences, University College London, London WC1E 6BT, UK.
Singapore's national myopia prevention efforts have largely focused on school vision screening and public education on outdoor activities in the past two decades. Given the emergence of evidence-based myopia interventions, this policy review and analysis investigates the potential benefits and drawbacks of optometrist prescribing privileges as it has been proposed to reduce the barriers to access effective interventions, such as combined therapy (e.g.
View Article and Find Full Text PDFChildren (Basel)
December 2024
School of Optometry and Vision Science, University of Bradford, Bradford BD7 1DP, UK.
Background/objectives: Perceptions and barriers to myopia management (MM) in childhood have not been fully explored within some countries, including the UK, where there is minimal public health education on myopia.
Methods: The aim of this mixed-methods study was to explore perceptions of myopia and MM interventions using focus groups and a survey to obtain qualitative and quantitative data. Topics included the understanding of myopia, perceptions of MM, considerations when initiating MM, lifestyle risk factors, and barriers to uptake of intervention.
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