AI Article Synopsis
- The study examined gender differences in demographic and clinical characteristics among 634 patients with HBV-related liver diseases.
- Results indicated that males were more likely to have specific factors such as employment, lower income, current alcohol use, and severe liver conditions like cirrhosis and hepatocellular carcinoma.
- The findings suggest that healthcare approaches should consider these gender-specific differences to improve treatment and prevention strategies for HBV-related liver diseases.
Article Abstract
Background: The gender differences in demographic and clinical characteristics were examined in patients with hepatitis B virus (HBV)-related liver diseases.
Methods: Overall, 634 patients (44.7 ± 13.8 years) were consecutively included. Data of demographic and clinical characteristics were collected during an assessment interview. Comparisons between male and female patients in terms of demographic and clinical data were carried out using univariate analyses. The independent associations between the demographic and clinical variables and gender were examined with either logistic regression or analysis of covariance as appropriate.
Results: The study sample consisted of 452 male and 182 female patients. Multiple logistic regression analyses revealed that being employed (OR = 3.4), personal monthly income <3,000 yuan (OR = 0.3), being current alcohol users (OR = 6.4), Cirrhosis (OR = 5.9), Hepatocellular Carcinoma (HCC) (OR = 8.5) and having less severe insomnia (OR = 0.6) were independently associated with male gender. The analysis of covariance revealed that after controlling for other potential confounding variables, later onset of HBV-related diseases ( = 4.5, = 0.03) and older age ( = 6.7, = 0.009) were independently associated with male gender.
Conclusions: Given the significant clinical differences in male and female patients with HBV-related liver diseases, more attention should be given to gender-specific treatment and prevention for this population.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359133 | PMC |
| http://dx.doi.org/10.7717/peerj.13828 | DOI Listing |
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