This study evaluates the in vitro antioxidant and immunomodulation activities of essential oils isolated from an anti-upper respiratory tract infection (URTI) formulation with a view to their therapeutic potential. The chemical components of the essential oil were analysed by gas chromatography-mass spectrometry (GC-MS). The antioxidative activity of the oils was investigated with regard to their ability to scavenge DPPH, ABTS, and hydroxyl free radical (•OH). Their immunostimulatory activities were determined using murine macrophage cells. The main components of the oil with pharmacological and biological activities include 1,8-eucalyptol (42.9%), patchouli alcohol (19.9%), trans-erinolide (9.2%), and guaiacol (5%). The oils displayed high DPPH, ABTS, and hydroxyl radical scavenging activities and anti-inflammatory activities by reducing tumour necrosis factor- (TNF-) and interleukin-6 (IL-6) production. The results indicate that essential oils have the potential to be used in products for anti-URTI treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357706 | PMC |
| http://dx.doi.org/10.1155/2022/7297499 | DOI Listing |
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