AI Article Synopsis
- Microbial identification traditionally used phenotypic methods, but newer technologies like VITEK-2 and MALDI-TOF MS are increasingly adopted in labs.
- The study aimed to compare the effectiveness of these two methods for routine identification of microorganisms.
- Both methods demonstrated high accuracy, identifying 96% (MALDI-TOF MS) and 97% (VITEK-2) of isolates, with MALDI-TOF MS offering quicker results, marking a significant advancement in clinical microbiology.
Article Abstract
Bacground: Microbial Identification was done by phenotypic methods. VITEK-2 and Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) are now being increasingly used in laboratories.
Objectives: To compare and evaluate the usefulness of MALDI-TOF MS and VITEK-2 in routine microbial identification.
Methods: The performances of MALDI-TOF MS and VITEK 2 were compared for identifying microorganisms.
Results: MALDI- TOF MS and VITEK-2 correctly identified 96 % (96/100) and 97% (97/100) of the isolates upto the genus level.
Conclusion: MALDI TOF MS and VITEK -2 gave comparable identification and error rates. The rapid reduction in turnaround time with MALDI TOF is a significant game-changer in the field of clinical microbiology.
Funding: State Board of Medical Research (SBMR).
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334958 | PMC |
| http://dx.doi.org/10.4314/gmj.v55i4.12 | DOI Listing |
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