AI Article Synopsis
- This study investigates the influence of ethnicity on the risk of out-of-hospital cardiac arrest (OHCA) among Danish immigrants from various regions between 2001 and 2020.
- It finds that immigrants from African, Arabic, and Eastern European backgrounds have a higher risk of OHCA, while those from Latin America have a lower risk.
- The results underline the importance of considering ethnicity alongside traditional risk factors and socioeconomic status in understanding OHCA incidence.
Article Abstract
Background: Ethnicity might impact out-of-hospital cardiac arrest (OHCA) risk, but it has scarcely been studied in Europe. We aimed to assess whether ethnicity influenced the risk of OHCA of cardiac cause in Danish immigrants and its interplay with risk factors for OHCA and socioeconomic status.
Methods: This nationwide study included all immigrants between 18 and 80 years present in Denmark at some point between 2001 and 2020. Regions of origin were defined as Africa, Arabic countries, Asia, Eastern Europe, Latin America, and Western countries. OHCAs with presumed cardiac cause were identified from the Danish Cardiac Arrest Registry.
Findings: Overall, among 1,011,565 immigrants, a total of 1,801 (0.2%) OHCAs (median age 64 (Q1-Q3 53-72) years, 72% males) occurred. The age- and sex- standardized (reference: Western countries) incidence of OHCA (/1,00,000 person-years) was 34.6 (27.8-43.4) in African, 34.1 (30.4-38.4) in Arabic, 33.5 (29.3-38.2) in Asian, 35.6 (31.9-39.6) in Eastern European, and 16.2 (9.0-27.2) in Latin American immigrants. When selecting Western origin as a reference, and after adjusting on OHCA risk factors, Arabic (HR 1.18, 95%CI 1.04-1.35; =0.01), Eastern European (HR 1.28, 95%CI 1.13-1.46; <0.001), and African origin (HR 1.34, 95%CI 1.10-1.63; <0.01) were associated with higher risk of OHCA, whereas Latin American origin (HR 0.58, 95%CI 0.35-0.0.96; =0.03) was associated with lower risk of OHCA. Comparable results were observed when adjusting on education level and economic status.
Interpretation: This study emphasizes that ethnicity is associated with OHCA risk, even when considering traditional cardiac arrest risk factors.
Funding: R Garcia received a grant from the for his post-doctoral fellowship and this work was supported by the (grant# 31364).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361311 | PMC |
| http://dx.doi.org/10.1016/j.lanepe.2022.100477 | DOI Listing |
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