Spectroscopic Studies of Mononuclear Molybdenum Enzyme Centers.

Molecules

Department of Biochemistry, Boyce Hall 1463, University of California, Riverside, CA 82521, USA.

Published: July 2022

A concise review is provided of the contributions that various spectroscopic methods have made to our understanding of the physical and electronic structures of mononuclear molybdenum enzymes. Contributions to our understanding of the structure and function of each of the major families of these enzymes is considered, providing a perspective on how spectroscopy has impacted the field.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370002PMC
http://dx.doi.org/10.3390/molecules27154802DOI Listing

Publication Analysis

Top Keywords

mononuclear molybdenum
8
spectroscopic studies
4
studies mononuclear
4
molybdenum enzyme
4
enzyme centers
4
centers concise
4
concise review
4
review provided
4
provided contributions
4
contributions spectroscopic
4

Similar Publications

Construction and Function of Thiolate-Bridged Diiron NH Nitrogenase Model Complexes.

Acc Chem Res

July 2024

State Key Laboratory of Fine Chemicals, Frontier Science Center for Smart Materials, Dalian University of Technology, Dalian 116024, P. R. China.

Article Synopsis
  • * Most studies have concentrated on single molybdenum or iron sites for nitrogen activation, while the potential of bi- or multimetallic centers is understudied, despite recent biochemical models suggesting their viability.
  • * This research focuses on creating thiolate-bridged diiron complexes as nitrogenase models to explore nitrogen reduction pathways, ultimately demonstrating the first complex capable of catalyzing the breakdown of hydrazine into ammonia.
View Article and Find Full Text PDF

This study aimed to synthesize molybdenum complexes coordinated with an aroyl hydrazone-type ligand (HL), which was generated through the condensation of 2-hydroxy-5-nitrobenzaldehyde with benzhydrazide. The synthesis yielded two types of mononuclear complexes, specifically [MoO(L)(MeOH)] and [MoO(L)(HO)], as well as a bipyridine-bridged dinuclear complex, [(MoO(L))(4,4'-bpy)]. Those entities were thoroughly characterized using a suite of analytical techniques, including attenuated total reflectance infrared spectroscopy (IR-ATR), elemental analysis (EA), thermogravimetric analysis (TGA), and single-crystal X-ray diffraction (SCXRD).

View Article and Find Full Text PDF

The reaction of molybdenum complexes with a tris(pyrazolyl)borate ligand (EtN[TpMo(CO)] and EtN[Tp*Mo(CO)] (Tp = hydridotris(pyrazolyl)borate, Tp* = hydridotris(3,5-dimethylpyrazolyl)borate)) and InBr at a 1:1 molar ratio afforded molybdenum-indane complexes (EtN[TpMo(CO)(InBr)] and EtN[Tp*Mo(CO)(InBr)] ). In addition, tungsten-indane complexes, EtN[TpW(CO)(InBr)] and EtN[Tp*W(CO)(InBr)] , were obtained by the reaction of corresponding tungsten complexes. Complex reacted with HO to form the hydrido complex Tp*W(CO)H, in which the W-In bond was cleaved.

View Article and Find Full Text PDF

Dynamics and Coordination of a PN Ligand - from Twisted Conformation to Chelation.

Chemistry

April 2024

Bioinorganic Chemistry, Institute of Biochemistry, University of Greifswald, 17489, Greifswald, Germany.

Based on their general spacial flexibility, their Lewis and Brønsted basicity, and ability to mimic second sphere effects the 1,5-diaza-3,7-diphosphacyclooctane ligand family and their complexes have regained substantial scientific interest. It was now possible to structurally analyze a recently reported member of this family with p-tolyl and t-butyl substituents on P and N, respectively, (P N ). Notably, the ligand crystallizes with a 'twisted' backbone.

View Article and Find Full Text PDF

A series of polynuclear, dinuclear, and mononuclear Mo(VI) complexes were synthesized with the hydrazonato ligands derived from 5-methoxysalicylaldehyde and the corresponding hydrazides (isonicotinic hydrazide (HL), nicotinic hydrazide (HL), 2-aminobenzhydrazide (HL), or 4-aminobenzhydrazide (HL)). The metallosupramolecular compounds obtained from non-coordinating solvents, [MoO(L)] ( and ) and [MoO(L)] ( and ), formed infinite structures and metallacycles, respectively. By blocking two coordination sites with cis-dioxo ligands, the molybdenum centers have three coordination sites occupied by the donor atoms from the rigid hydrazone ligands and one by the N atom of pyridyl or amine-functionalized ligand subcomponents from the neighboring Mo building units.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!