This study aimed to investigate the effects of role conflict and professional autonomy on the role performance of patient safety coordinators in small and medium-sized hospitals in Korea. The participants in this cross-sectional study were 121 patient safety coordinators in general hospitals or hospitals with more than 100−300 beds. Data were collected through an online survey for about three weeks in February 2022. The variables were role conflict, professional autonomy, and role performance. In the data analysis, we employed the t-test, ANOVA, correlation, and multiple regression methods. Almost all (99.2%) of the participants were nurses. The lower the role conflict and the higher the professional autonomy, the better the role performance shown. As a result of analyzing the factors affecting role performance, the regression model was found to be significant (F = 6.988, p < 0.001). The most influential factor in role performance was professional autonomy (β = 0.279, p = 0.002). In conclusion, it is thought that systematic education and legal and institutional arrangements for independent roles and work regulations are needed to strengthen patient safety coordinators’ competency in small and medium-sized hospitals in Korea. This will improve the role performance of patient safety coordinators and create a better patient safety culture.
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http://dx.doi.org/10.3390/ijerph19159392 | DOI Listing |
Sci Rep
December 2024
Department of Orthopedics, The Second Affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
The DNA cross-link repair 1B (DCLRE1B) gene is involved in repairing cross-links between DNA strands, including those associated with Hoyeraal-Hreidarsson syndrome and congenital dyskeratosis. However, its role in tumours is not well understood. DCLRE1B expression profiles were examined in tumour tissues and normal tissues using TCGA, GTEx, and TARGET datasets.
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December 2024
School of Civil Engineering, Architecture and Environment, Hubei University of Technology, Wuhan, China.
The dolomite dust-emulsified asphalt composite (DAC) with excellent mechanical properties was successfully prepared using alkali activation. The effects of different alkali concentrations and emulsified asphalt contents on the mechanical properties of the materials were studied. And the micro-mechanisms of its mechanical performance changes were analyzed through SEM and XRD characterization.
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December 2024
Institute of Medical Sciences, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.
Astrocyte to neuron reprogramming has been performed using viral delivery of neurogenic transcription factors in GFAP expressing cells. Recent reports of off-target expression in cortical neurons following adeno-associated virus (AAV) transduction to deliver the neurogenic factors have confounded our understanding of the efficacy of direct cellular reprogramming. To shed light on potential mechanisms that may underlie the neuronal off-target expression of GFAP promoter driven expression of neurogenic factors in neurons, two regionally distinct cortices were compared-the motor cortex (MC) and medial prefrontal cortex (mPFC)-and investigated: (1) the regional tropism and astrocyte transduction with an AAV5-GFAP vector, (2) the expression of Gfap in MC and mPFC neurons; and (3) material transfer between astrocytes and neurons.
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December 2024
Molecular Biology and Genetics Laboratory (LGBM), UFMS - Federal University of Mato Grosso do Sul, Três Lagoas, Brazil.
Sickle cell anemia (SCA) is a monogenic blood disease with complex and multifactorial pathophysiology. The endocannabinoid system (ECS) could be a candidate for modulating SCA complications, such as priapism, as it has demonstrated an essential role in hematopoiesis, platelet aggregation, and immune responses. We evaluated the association of ECS-related single nucleotide polymorphisms (SNP) (FAAH rs324420, MAGL rs604300, CNR1 rs7766029, and CNR2 rs35761398) with priapism in a Brazilian SCA cohort.
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December 2024
Department of Medical and Surgical Sciences, Institute of Cardiology, University of Bologna, Policlinico S.Orsola-Malpighi, via Massarenti 9, Bologna, 40138, Italy.
Cardiac implantable electronic devices infections (CIEDI) are associated with poor survival despite the improvement in transvenous lead extraction (TLE). Aetiology and systemic involvement are driving factors of clinical outcomes. The aim of this study was to explore their contribute on overall mortality.
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