Lipoma and Its Doppelganger: The Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma.

Surg Clin North Am

Department of Surgery, University of Colorado, 12605 East 16th Avenue, Aurora, CO 80045, USA.

Published: August 2022

Lipomatous tumors are among the most common soft tissue lesions encountered by the general surgeon. Shared history and clinical presentation make differentiation between benign lipomas and low-grade liposarcomas a diagnostic dilemma. This article reviews the epidemiology, clinical history, diagnostic workup, management, natural history, and surveillance of benign lipomas and atypical lipomatous tumors/well-differentiated liposarcomas. Although it is important that aggressive, potentially malignant atypical lipomatous tumors and liposarcomas be managed in a multidisciplinary, preferably high-volume setting, it is equally as important for the nonspecialist general surgeon to be familiar with lipoma and its doppelganger-the well-differentiated liposarcoma.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.suc.2022.04.006DOI Listing

Publication Analysis

Top Keywords

atypical lipomatous
12
lipomatous tumors
8
general surgeon
8
benign lipomas
8
lipoma doppelganger
4
doppelganger atypical
4
lipomatous
4
lipomatous tumor/well-differentiated
4
tumor/well-differentiated liposarcoma
4
liposarcoma lipomatous
4

Similar Publications

Pleomorphic adenoma (PA), the most prevalent salivary gland tumor, exhibits a diverse histological spectrum characterized by epithelial, myoepithelial, and mesenchymal patterns, and secretory products. However, a subset of PAs presents microscopic features suggestive of malignancy, leading to challenging and potentially significant diagnostic pitfalls. A comprehensive retrospective analysis was conducted on the Salivary Gland Tumor Registry, compiled by the authors.

View Article and Find Full Text PDF

A lipoblastoma is a benign tumor of adipocytes originating from embryonic white fat and occurs in the pediatric population. Congenital lipoblastomas, however, are rare, and the incidence of these tumors in neonates is unknown. Due to their rare presentation, congenital oral lipoblastomas can, firstly, pose diagnostic challenges for the pediatrician and must be differentiated from the more commonly seen oral lesions in the newborn and other rare malignant growths.

View Article and Find Full Text PDF
Article Synopsis
  • Liposarcomas are the most common type of soft tissue sarcoma, primarily found in deep tissues and the retroperitoneum.
  • They include various classifications such as atypical lipomatous tumors, well-differentiated liposarcoma (WDL), dedifferentiated liposarcoma (DDL), myxoid liposarcoma, and pleomorphic liposarcoma.
  • DDL is especially common in the retroperitoneum and can have both well-differentiated lipomatous and dedifferentiated components, sometimes resembling other aggressive tumors, and can even differentiate into several other cancer types or form bone tissue.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to analyze the epidemiology of patients with musculoskeletal tumors treated at a reference hospital from 2009 to 2022.
  • A total of 1978 patients were examined, revealing that 1477 (74.67%) had sarcomas, categorized into 446 bone tumors and 1,031 soft tissue tumors.
  • The findings highlighted the most common tumors, including enchondroma for benign bone tumors, osteosarcoma for malignant, lipomas for benign soft tissue tumors, and sarcomas of uncertain differentiation as the most frequent malignant soft tissue tumors.
View Article and Find Full Text PDF

Sarcomas are a heterogeneous group of neoplasms that develop from bone and soft tissue. Approximately 80% of sarcomas affect soft tissue, with liposarcoma being one of the most common types, accounting for approximately 13-20% of all soft-tissue sarcomas. Per the World Health Organization, liposarcoma can be broadly classified into four different subtypes based on histologic examination: well-differentiated liposarcoma (WDLS)/atypical lipomatous tumors (ALT), dedifferentiated liposarcoma (DDLS), myxoid liposarcoma (MLS), and pleomorphic liposarcoma (PLS).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!