Unlabelled: Closed-loop stimulation (CLS; BIOTRONIK SE & Co. KG, Berlin, Germany) is a rate-responsive algorithm that analyzes intracardiac impedance trends using a standard lead placed in the right ventricle. It is unknown whether CLS could perform adequately with His bundle (HB) lead placement, as contractility dynamics may be attenuated in this region compared to the right ventricle apex.We performed hand-grip, mental, and bicycle exercise tests in a patient with brady atrial fibrillation and permanent HB pacing. The CLS algorithm responded with an appropriate heart rate to mental and physical tests.
Learning Objective: A combination of permanent His bundle and closed-loop stimulation-driven pacing may be a valid and physiological option for atrial fibrillation patients with chronotropic incompetence.
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http://dx.doi.org/10.1016/j.jccase.2022.03.015 | DOI Listing |
Background: Recent advancements in molecular positron emission tomography (PET) enable precise tracking of tau pathology in Alzheimer's disease (AD). Tau pathology typically begins focally in the medial temporal lobe, rapidly expanding due to amyloid-β (Aβ) influence. This expansion may lead to neurodegeneration along connected pathways to the tau epicenters, resulting in cognitive decline.
View Article and Find Full Text PDFExpert Rev Med Devices
January 2025
Cardiology Unit, "Card. G. Panico" Hospital, Tricase (Le), Italy.
Introduction: In patients with symptomatic, refractory atrial fibrillation the ablate and pace (A&P) strategy (pacemaker implantation followed by atrio-ventricular junction ablation (AVJA)) is superior to medical therapy in improving quality of life and prognosis. Despite its well-proven benefits, this invasive therapeutic option is still underutilized in clinical practice. The choice of pacing modality (right ventricular pacing, biventricular pacing, BVP, or conduction system pacing, CSP) is crucial and can have significant clinical implications.
View Article and Find Full Text PDFJBJS Essent Surg Tech
January 2025
The Ohio State University College of Medicine, Columbus, Ohio.
Background: An all-inside endoscopic flexor hallucis longus (FHL) tendon transfer is indicated for the treatment of chronic, full-thickness Achilles tendon defects. The aim of this procedure is to restore function of the gastrocnemius-soleus complex while avoiding the wound complications associated with open procedures.
Description: This procedure can be performed through 2 endoscopic portals, a posteromedial portal (the working portal) and a posterolateral portal (the visualization portal).
J Comput Assist Tomogr
November 2024
From the Department of Radiology.
Numerous obstacles confront radiologists interested in the use of artificial intelligence (AI) models within the field of radiology. For example, discrepancies between the radiologist's and an AI developer's hardware and software specifications pose a substantial hindrance to using AI models. Additionally, accessing and using GPU computers can lead to compatibility issues and add to these challenges.
View Article and Find Full Text PDFEur Heart J Case Rep
January 2025
Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Background: Left bundle branch block (LBBB) is a rare conduction disorder in athletes associated with ventricular dyssynchrony, which can lead to left ventricular systolic dysfunction and exercise intolerance. Inappropriate sinus tachycardia (IST) is characterized by an excessive heart rate (HR) that is not related to physiological needs, often resulting in reduced exercise capacity. Managing these conditions in athletes can be challenging, as standard treatments like beta-blockers and ivabradine, while effective in controlling HR, are described to be associated with a reduction in maximal exercise performance.
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