Spontaneous renal parenchymal rupture is a rare clinical emergency. The formation of benign and malignant tumors is the most common underlying cause of spontaneous rupture of renal parenchyma. To the best of our knowledge, 15 cases of renal parenchymal rupture have been reported to date. This report describes a rare case of renal parenchyma rupture in the lower left kidney caused by kidney calculi. Furthermore, previously published cases and articles were reviewed. The patient underwent four extracorporeal shockwave lithotripsy procedures within 2 years. The renal parenchyma rupture caused by the stones was successfully treated by removing the stones and repairing the kidney. However, a large hematoma was discovered around the lower pole of the left kidney, suggesting the possibility of a renal tumor. Therefore, radical nephrectomy was performed. Postoperative pathology revealed the lesion to be consistent with an intrarenal stone, where no malignancy, infection or vascular disease was observed. The present case highlights the requirement to also take into account the patient's clinical history in cases where imaging cannot completely identify the underlying cause of renal parenchymal rupture. Accurate identification of the underlying etiology of spontaneous renal rupture may determine the best treatment for the patient. The purpose of the present report is to facilitate the identification of the disease and reduce the rate of clinical misdiagnosis.
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http://dx.doi.org/10.3892/etm.2022.11525 | DOI Listing |
Clin Chim Acta
December 2024
Departments of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address:
Background: To explore the underlying causes of significant fluctuations in creatinine levels within three days due to transient and severe uric acid elevation, and to provide evidence for the interpretation of abnormal test results and clinical diagnosis and management.
Methods: The issues were resolved by retesting the samples, comparing results across different detection platforms, and analyzing the reaction curve. We comprehensively reviewed patients' general conditions, imaging examinations, and treatments.
Front Pharmacol
December 2024
Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Introduction: With the increasing prevalence of hypertension, the incidence of kidney diseases is also increasing, resulting in a serious public burden. Jiangya Tongluo decoction (JYTL), a recognized prescription in traditional Chinese medicine (TCM), is commonly used to calm an overactive liver and reduce excess yang, while also promoting blood flow to alleviate obstructions in the meridians. Previous research has indicated that JYTL may help mitigate kidney damage caused by hypertension; however, the underlying mechanisms have not been thoroughly assessed.
View Article and Find Full Text PDFJ Pediatr Urol
December 2024
Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.
Introduction: There exists a prevailing concern regarding the heightened susceptibility of women with a solitary kidney to unfavorable consequences during pregnancy. Irrespective of the underlying etiology, individuals with a solitary kidney are advised to have regular annual screenings for blood pressure and urinalysis due to their increased susceptibility to developing proteinuria, hypertension, and renal failure.
Objective: To investigate the risk of adverse pregnancy outcomes in women with a maternal solitary kidney by comparing maternal and fetal outcomes to those of healthy pregnant women.
Intern Med J
December 2024
Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Excipients have been identified as 'inert' substances that often enhance the non-pharmacological aspects of a medication. However, recent clinical evidence elucidates their potential in inducing anaphylaxis and indicates that they are often overlooked as potential allergens in routine clinical practice. The aim of the study was to assimilate published evidence on excipient-induced allergies associated with the use of oral medications and to underline their potential as potent allergens.
View Article and Find Full Text PDFResusc Plus
December 2024
Department of Critical Care Medicine, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Background: Hypoxic hepatitis (HH) is commonly seen in critically ill patients, such as those with cardiac shock, sepsis, and respiratory failure. However, data are limited regarding its impact on the prognosis of patients with cardiac arrest (CA).
Methods: We conducted a systematic review and meta-analysis of studies from PubMed, EMBASE, and the Cochrane Library from inception to July 30, 2024.
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