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Multicenter, PrOspective, Randomized, Controlled Trial Comparing GenIcular Artery EmbOlization Using Embosphere Microspheres to Corticosteroid iNjections for the Treatment of Symptomatic Knee Osteoarthritis: MOTION Study Protocol Summary.
Cardiovasc Intervent Radiol
March 2025
Prostate Centers USA, LLC, Falls Church, VA, USA.
Purpose: Corticosteroid injections are commonly used to treat symptomatic knee osteoarthritis; however, pain relief is usually transient. Genicular artery embolization (GAE) has shown promise as an effective minimally invasive intervention to alleviate symptomatic knee osteoarthritis. The MOTION study is being conducted to compare outcomes following GAE versus corticosteroid injection.
View Article and Find Full Text PDFA 77 year old man with recurrent lower extremity thrombosis presented with acute onset shortness of breath and new onset hypoxemia three days after prostatectomy for adenocarcinoma of the prostate. He had been off anticoagulation during the perioperative period. In addition to his new diagnosis of prostate cancer he also had a remote history of treated non-invasive melanoma.
View Article and Find Full Text PDFTadalafil Use in Cardiovascular Disease.
Cardiol Rev
February 2025
From the Department of Medicine, School of Medicine, New York Medical College, Valhalla, NY.
Tadalafil is a phosphodiesterase inhibitor currently approved for use in erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). While tadalafil's benefits in ED and BPH have been well-established for years, its benefits in PAH were identified only recently in major clinical trials, resulting in the recent approval of a single-tablet, combination therapy of tadalafil with an endothelin receptor antagonist for PAH. With Tadalafil's cardiovascular benefits in ED, BPH, and PAH, clinical researchers have begun investigating whether tadalafil's use extends to other cardiovascular diseases, especially heart failure (HF), an emerging epidemic in medicine.
View Article and Find Full Text PDFLong-term functional and prognostic outcomes of robotic intersphincteric resection for treating low rectal cancer: a single-center retrospective study.
Int J Colorectal Dis
February 2025
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, China.
Objective: Intraoperative and postoperative data collected from patients with low rectal cancer who had undergone robotic and laparoscopic intersphincteric resection (ISR) procedures were retrospectively analyzed to evaluate factors linked to anastomotic leakage and postoperative recovery of urinary function, bowel control, and long-term prognosis.
Method: This single-center study enrolled patients with low rectal cancer who had undergone robotic ISR (n = 150) or laparoscopic ISR (n = 150) from January 2016 to July 2019.
Result: The respective mean tumor distances from the anal margin in the robotic and laparoscopic ISR groups were 3.
Genitofemoral nerve course and branching variations: what we see during laparoscopic extended pelvic lymph-node dissection in radical prostatectomy for prostate cancer and how to avoid intraoperative lesions? A retrospective analysis.
Folia Morphol (Warsz)
February 2025
Department of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, Poland.
Background: The genitofemoral nerve is the most variable nerve of the lumbar plexus, in terms of its course and bifurcation, thus it must be taken into consideration during extended pelvic lymph node dissection. Its borders, during robotic, laparoscopic or open radical prostatectomy for intermediate or high-grade prostate cancer, have long been defined and must be usually respected; the genitofemoral nerve represents the extended pelvic lymph-node dissection lateral boundary and may vary from case to case putting its integrity at risk.
Materials And Methods: For the first time, here the authors report genitofemoral nerve branching pattern data obtained extended pelvic lymph node dissection during videolaparoscopic radical prostatectomyand propose a further sub-classification to identify the exact genitofemoral nerve bifurcation point in correlation with the injury risk.
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