Cytochrome bc1 Complex: Potential Breach to Improve the Activity of Phenazines on .

The effects of the natural pesticides, phenazines, were reported to be limited by some tolerant metabolism processes within . Our previous studies suggested that the functional cytochrome bc1 complex, the indispensable component of the respiration chain, might participate in tolerating phenazines in . In this study, the cytochrome bc1 mutants of pv. () and pv. (), which exhibit different tolerance abilities to phenazines, were constructed, and the cytochrome bc1 complex was proven to partake a critical and conserved role in tolerating phenazines in . In addition, results of the cytochrome mutants suggested the different functions of the various cytochrome proteins in and that the electron channeled by the cytochrome bc1 complex to cytochrome C4 is the key to reveal the tolerance mechanism. In conclusion, the study of the cytochrome bc1 complex provides a potential strategy to improve the activity of phenazines against .