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Similar pipeline experiment and disaster control emergency plan of updraft airflow fire in mine.
Sci Rep
December 2024
College of Safety Science and Engineering, Liaoning Technical University, 47 Zhonghua Road, Xihe District, Fuxin City, 123000, Liaoning Province, China.
Based on the engineering example of Linsheng coal mine, this paper uses TF1M3D computer simulation platform to systematically analyze the process of smoke flow spreading and air flow disorder disaster from the perspective of the whole mine network, and puts forward corresponding plans and measures. A small scale similar experiment was carried out to study the updraft flow fire in the mine. Through the analysis of the collected experimental data, the variation law of the air volume of the fire source in the main air path, side branch road and total air path with different air volume and the variation characteristics of the temperature at the monitoring point with time were obtained under different air volume conditions, and the critical air volume was fitted as 1.
View Article and Find Full Text PDFThe role of KRT18 in lung adenocarcinoma development: integrative bioinformatics and experimental validation.
Discov Oncol
December 2024
School of Pharmacy, Shaoyang University, Shaoyang, 422000, Hunan, China.
Lung adenocarcinoma (LUAD) represents one of the most common subtypes of lung cancer with high rates of incidence and mortality, which contributes to substantial health and economic demand across the globe. Treatment today mainly consists of surgery, radiotherapy, and chemotherapy, but their efficacy in advanced stages is often suboptimal and emphasizes the clear need for new biomarkers and therapeutic targets. Using comprehensive bioinformatics analyses consisting of the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), Human Protein Atlas (HPA) and Clinical Proteomic Tumor Analysis Consortium (CPTAC), immune infiltration analysis and functional enrichment analysis, and single-cell analysis, we examined the potential of keratin 18 (KRT18) as a candidate biomarker in advanced LUAD.
View Article and Find Full Text PDFA PDA@ZIF-8-Incorporated PMIA TFN-FO Membrane for Seawater Desalination: Improving Water Flux and Anti-Fouling Performance.
Membranes (Basel)
December 2024
Shanghai Electronic Chemicals Innovation Institute, East China University of Science and Technology, Shanghai 200237, China.
Forward osmosis (FO) technology, known for its minimal energy requirements, excellent resistance to fouling, and significant commercial potential, shows enormous promise in the development of sustainable technologies, especially with regard to seawater desalination and wastewater. In this study, we improved the performance of the FO membrane in terms of its mechanical strength and hydrophilic properties. Generally, the water flux () of polyisophenylbenzamide (PMIA) thin-film composite (TFC)-FO membranes is still inadequate for industrial applications.
View Article and Find Full Text PDFThe relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.
Front Cardiovasc Med
December 2024
Cardiology Department, Guang'anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing, China.
Objective: Inflammatory factors play a crucial role in the onset and progression of heart failure. To further explore the causal relationship between inflammatory factors and heart failure, we employed bidirectional Mendelian randomization analysis to investigate the causal links between 91 inflammatory cytokines and heart failure.
Methods: We conducted our study using the bidirectional Mendelian randomization approach.
A Quantum Chemistry Insight into the Potential Role of the Singlet Oxygen-Acetone System as a Source for Production of Stable Secondary Organic Aerosols through a Multiwell Multipath Reaction.
J Phys Chem A
December 2024
Department of Chemistry, University of Zanjan, PO Box 38791-45371 Zanjan, Iran.
The high abundance of acetone ((CH)C═O), which makes it a good candidate for oxygenated molecules, and the high reactivity of oxygen atoms in the first excited state O(D) are two well-known facts in the chemistry of the atmosphere. In this research, we prove that the singlet oxygen and acetone system is capable of proceeding through multiwell multipath reactions, leading to the production of several organic aerosols. Hence, the nature of species released by the (CH)C═O + O(D) reaction to air can be clarified by profound attention to the possible routes.
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