Anti-phospholipase A2 Receptor Antibody-Positive Membranous Glomerulopathy due to Anti-Koch's Therapy in a Tuberculosis Patient.

Saudi J Kidney Dis Transpl

Department of Medicine, Jawaharlal Nehru Medical College, Sawangi, Wardha; Department of Medicine, Saraswati Kidney Care Center, Nagpur, Maharashtra, India.

Published: August 2022

AI Article Synopsis

  • Tuberculosis (TB) can lead to a specific kidney condition called glomerulonephritis, which has symptoms like blood in urine, protein in urine, swelling, high blood pressure, or kidney failure, making it hard to differentiate from other kidney issues.
  • Membranous nephropathy (MN), a type of kidney disease, is rare in TB patients.
  • A case study highlights a 30-year-old woman with TB who developed MN after starting treatment for TB, which improved after she completed her anti-TB therapy.

Article Abstract

Tuberculosis (TB)-associated glomerulonephritis is difficult to diagnose that usually presents with hematuria, proteinuria, edema, hypertension, or renal insufficiency, which is similar to symptoms of primary glomerulonephritis. Membranous nephropathy (MN) is uncommonly seen in TB patients. We report a case of a 30-year-old female with Koch's chest who developed anti-phospholipase A2 receptor antibody-positive MN after initiation of anti-Koch's therapy and resolved after completion of anti-Koch's therapy.

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Source
http://dx.doi.org/10.4103/1319-2442.352444DOI Listing

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