Purpose: Accurate assessment of the percentage of total body surface area (%TBSA) burned is crucial in managing burn injuries. It is difficult to estimate the size of an irregular shape by inspection. Many articles reported the discrepancy of estimating %TBSA burned by different doctors. We set up a system with multiple deep learning (DL) models for %TBSA estimation, as well as the segmentation of possibly poor-perfused deep burn regions from the entire wound.
Methods: We proposed boundary-based labeling for datasets of total burn wound and palm, whereas region-based labeling for the dataset of deep burn wound. Several powerful DL models (U-Net, PSPNet, DeeplabV3+, Mask R-CNN) with encoders ResNet101 had been trained and tested from the above datasets. With the subject distances, the %TBSA burned could be calculated by the segmentation of total burn wound area with respect to the palm size. The percentage of deep burn area could be obtained from the segmentation of deep burn area from the entire wound.
Results: A total of 4991 images of early burn wounds and 1050 images of palms were boundary-based labeled. 1565 out of 4994 images with deep burn were preprocessed with superpixel segmentation into small regions before labeling. DeeplabV3+ had slightly better performance in three tasks with precision: 0.90767, recall: 0.90065 for total burn wound segmentation; precision: 0.98987, recall: 0.99036 for palm segmentation; and precision: 0.90152, recall: 0.90219 for deep burn segmentation.
Conclusion: Combining the segmentation results and clinical data, %TBSA burned, the volume of fluid for resuscitation, and the percentage of deep burn area can be automatically diagnosed by DL models with a pixel-to-pixel method. Artificial intelligence provides consistent, accurate and rapid assessments of burn wounds.
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http://dx.doi.org/10.1016/j.burns.2022.07.006 | DOI Listing |
Int J Biol Macromol
December 2024
Nano Drug Delivery Systems (NDDS), Cancer Biology Division, Rajiv Gandhi Centre for Biotechnology, Thycaud P.O, Poojappura, Thiruvananthapuram, Kerala 695014, India. Electronic address:
Severe burns pose significant threats to patient well-being, characterized by pain, inflammation, bacterial infection, and extended recovery periods. While exosome-loaded hydrogels have demonstrated considerable promise in wound healing, current formulations often fall short of achieving optimal therapeutic efficacy for burn wounds due to challenges related to their adaptability to wound shape and limited anti-bacterial capabilities. In this study a novel exosome laden sprayable thermosensitive polysaccharide-based hydrogel (ADA-aPF127@LL18/Exo) comprising alginate dialdehyde (ADA) and aminated Pluronic F127 (aPF127) was fabricated via Schiff base reaction.
View Article and Find Full Text PDFOral Surg Oral Med Oral Pathol Oral Radiol
October 2024
Department of Translational Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Objective: Artificial intelligence (AI) has been increasingly utilized in diagnosis of skeletal deformities, while its role in treatment planning and outcome prediction of jaw corrective surgeries with 3-dimensional (3D) imaging remains underexplored.
Methods: The comprehensive search was done in PubMed, Google scholar, Semantic scholar and Cochrane Library between January 2000 and May 2024. Inclusion criteria encompassed studies on AI applications in treatment planning and outcome prediction for jaw corrective surgeries using 3D imaging.
bioRxiv
December 2024
Lundbeck Foundation GeoGenetics Center, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
The Indo-European languages are among the most widely spoken in the world, yet their early diversification remains contentious. It is widely accepted that the spread of this language family across Europe from the 5th millennium BP correlates with the expansion and diversification of steppe-related genetic ancestry from the onset of the Bronze Age. However, multiple steppe-derived populations co-existed in Europe during this period, and it remains unclear how these populations diverged and which provided the demographic channels for the ancestral forms of the Italic, Celtic, Greek, and Armenian languages.
View Article and Find Full Text PDFJ Endovasc Ther
December 2024
Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece.
Purpose: We sought to investigate the mid-term and long-term efficacy of 1470 nm endovenous laser ablation (EVLA).
Material And Methods: We conducted a systematic research on PubMed, Scopus, and Web of science for articles published by January 2024. The primary endpoints were truncal vein and great saphenous vein (GSV) occlusion.
Ann Plast Surg
January 2025
From the Department of Burn and Plastic, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Background: Deep burns to the upper abdomen that involve the submammary fold can lead to downward contracture and may cause significant asymmetry in a single breast, which can cause serious aesthetic and psychological problems, especially when they occur during childhood or before puberty. The objective of this study was to establish a practical treatment approach for postburn unilateral breast reconstruction after downward contracture.
Method: We conducted this retrospective review of patients with postburn unilateral breast deformity who underwent reconstruction using the expanded lateral thoracic flap and torso advancement flap from 2016 through 2021.
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