Background & Aims: As the global prevalence of non-alcoholic fatty liver disease (NAFLD) continues to rise, ubiquity of alcohol use has also prompted discussion regarding the potential interactions between the two. This study aims to examine the effects of modest alcohol consumption on the prevalence and complications of NAFLD in a multi-ethnic population.
Methods: This study analyses the 2017-2018 cycles of NHANES that examined liver fibrosis and steatosis with vibration controlled transient elastography. A coarsened exact matching was conducted to reduce confounding. Logistic regression was done with a multivariate model to assess the relationship between alcohol consumption (modest drinkers and non-drinkers) and risk of NAFLD and its complications.
Results: 2,067 individuals were found to have NAFLD and 284 NAFLD patients had a total history of alcohol abstinence. After coarsened exact matching, the prevalence of NAFLD was 49% (CI: 0.41 - 0.58) in non-drinkers and 33% (CI: 0.26 - 0.41) in modest drinkers. Non-drinkers had twice the odds of NAFLD compared to modest drinkers (OR: 1.99, CI: 1.22 - 3.22, <.01) after adjustment for confounders. There were no significant differences in the odds of significant fibrosis, advance fibrosis, cirrhosis, cardiovascular disease and stroke between non-drinkers and modest drinkers. The odds of malignancy in non-drinkers were almost significantly less than modest drinkers (OR: 0.28, CI:0.08 - 1.02, =.053).
Conclusion: Interestingly, modest alcohol consumption is associated with decreased odds of NAFLD. Further investigations are required to examine the relationship between alcohol consumption and NAFLD and subsequently the potential impact on NAFLD management.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/00365521.2022.2105168 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Delay discounting of rewards and losses, alcohol use, and the influence of socioeconomic factors: A cross-sectional online study in frequent drinkers.
Alcohol Clin Exp Res (Hoboken)
December 2024
Institute of Psychology, University of Heidelberg, Heidelberg, Germany.
Background: Delay discounting describes the devaluation of future outcomes over time and is a popular behavioral construct in addiction research. Prior studies show modest yet consistent associations between problematic alcohol use and delayed reward discounting (DRD). However, the potential confounding influence of socioeconomic status (SES, e.
View Article and Find Full Text PDFPotential impact of alcohol calorie labelling on the attitudes and drinking behaviour of hazardous and low-risk drinkers in England: a national survey.
BMJ Open
September 2024
Department of Behavioural Science and Health, University College London, London, UK.
Objectives: We investigated the hypothetical impact of mandatory alcohol calorie labelling, comparing non-drinkers, low-risk and hazardous drinkers in terms of attitudes, knowledge about calorie content and hypothetical behaviour changes should labelling be introduced.
Design: Cross-sectional national telephone survey.
Setting: Community-dwelling adults in England between November 2022 and January 2023.
Coffee, Phosphoinositide 3-Kinase Signaling Pathway, and Prostate Cancer: A Prospective Study in the Health Professionals Follow-Up Study.
J Acad Nutr Diet
January 2025
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Electronic address:
Article Synopsis
- Higher coffee consumption may be linked to a lower risk of aggressive prostate cancer, potentially through effects on the PI3K signaling pathway involved in cancer development.
- This study examined the relationship between prediagnostic coffee intake and various tumor markers in men with prostate cancer from a large cohort known as the Health Professionals Follow-Up Study.
- Results indicated that while most participants were coffee drinkers, the overall associations between coffee intake and tumor markers were weak, with only minimal differences observed in PI3K activation scores and angiogenesis markers depending on coffee consumption levels.
Exposure to preference-matched alcohol advertisements from national sports broadcasts increases short-term alcohol consumption inclinations in risky drinkers.
Health Promot J Austr
January 2025
School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Background: In Australia, sports broadcasting is afforded special alcohol advertising rights during daytime hours, which raises public health concerns, including short-term increases in alcohol consumption among the broad viewership of national sporting codes.
Methods: We conducted a content analysis across a sample of nationally televised finals matches (N = 16) from the Australian Football League (AFL) and the National Rugby League (NRL) to determine the prevalence of alcohol advertising video clips during these broadcasts. We also conducted an online experiment exposing participants (N = 345) to a randomly selected alcohol advertisement and measured the immediate effects on self-reported alcohol craving and drinking intentions.
A Pilot Study of a Quantitative Approach to Reduce Binge Drinking in Young Adults: Know Your Numbers.
J Stud Alcohol Drugs
November 2024
Department of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois.
Article Synopsis
- The study evaluated the effectiveness of a short-term "Know Your Numbers" (KYN) intervention aimed at reducing binge drinking among young adults, focusing on recruitment, retention, and acceptability.
- After a 4-week intervention, there was a notable increase in motivation to reduce drinking and a decrease in risky drinking behaviors, although no significant changes were observed in binge episodes or specific alcohol biomarker levels.
- Participants expressed satisfaction with the KYN approach but requested clearer connections between their alcohol scores and potential health impacts.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!