AI Article Synopsis
- Ingestion of leaves from the European yew tree can lead to severe heart issues, including fatal arrhythmias and cardiogenic shock, due to toxic alkaloids blocking important cardiac channels.
- A case study of a 39-year-old patient who experienced toxic cardiogenic shock from yew poisoning highlights the potential for recovery using venoarterial extracorporeal membrane oxygenation (VA-ECMO).
- This report underscores the importance of recognizing poisoning as a reversible cause of cardiac arrest and supports the early application of VA-ECMO in similar poisoning cases.
Article Abstract
Ingestion of leaves of the European yew tree () can result in fatal cardiac arrhythmias and acute cardiogenic shock. This cardiotoxicity derives from taxine alkaloids that block cardiac voltage-gated sodium and calcium channels. Prompt initiation of venoarterial extracorporeal membrane oxygenation is essential to bridge these critically ill patients to recovery, as there is no antidote available. We here report a 39-year old patient with toxic cardiogenic shock after yew poisoning, who was successfully rescued by venoarterial extracorporeal membrane oxygenation and had a full neurological recovery. This report emphasizes the role of intoxications as reversible causes of cardiac arrest and adds further evidence to the body of existing literature thus encouraging the early use of venoarterial extracorporeal membrane oxygenation in patients with yew poisoning and cardiogenic shock.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367666 | PMC |
| http://dx.doi.org/10.1080/19336950.2022.2104886 | DOI Listing |
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