Primary dentition takes the most important role in the development of permanent dentition. Primary second molars determine the eruption and position of permanent first molars. Early diagnosis and treatment could prevent the establishment of occlusal anomalies and deformities, therefore this study aimed to collect data about the prevalence of malocclusions based on the deciduous second molar terminal planes among the Tbilisi preschoolers. A total of 396 children aged 3-6 years, with an equal number of male and female subjects, were examined in kindergartens drawn from ten districts of Tbilisi, using the PPS (probability proportional to size) method. The relationship between distal surfaces of primary second molars was evaluated and recorded according to Baume's classification. The significance level is 0.05 for all statistical tests. Out of investigated preschoolers, 52.7% showed the flush terminal plane, followed by the distal step in 21.2% and mesial step in 26.1% of cases. There were no significant differences in genders. The most prevalent relationship between deciduous second molars was the flush terminal plane, with equal distribution in all age groups. The frequency of distal step decreased with age, more frequently recorded in the 3 to 4 year age group. The mesial step was mostly recorded in 3-4 and 5-6 year groups. The flush terminal plane is the most frequent molar relationship, followed by mesial and distal step. Prevalence of distal mesial step significantly decreased with age, while mesial step relationship showed the tendency to increase. The flush terminal plane showed little change with age.
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http://dx.doi.org/10.34172/joddd.2022.004 | DOI Listing |
J Am Heart Assoc
December 2024
Division of Cardiovascular Medicine, Brigham and Women's Hospital Harvard Medical School Boston MA USA.
Background: This study aims to characterize right ventricular dysfunction (RVD) in heart failure (HF) with preserved ejection fraction and understand the cumulative prognostic value of abnormal RV echocardiographic parameters in HF with preserved ejection fraction.
Methods And Results: Data from 809 patients in the PARAGON-HF (Prospective Comparison of Angiotensin Receptor-Neprilysin Inhibitor With Angiotensin-Receptor Blocker Global Outcomes in HF With Preserved Ejection Fraction) echocardiographic substudy (55% women, mean age 74±8 years) were analyzed. Correlates of RVD (defined as tricuspid annular plane systolic excursion <1.
Inorg Chem
December 2024
Department of Energy and Materials, Kindai University, 3-4-1 Kowakae, Higashi-Osaka, Osaka 577-8502 Japan.
Three distinct n-type semiconductors were derived from a platinum-trialkyl phosphine complex; to lower their LUMO levels, various indene derivatives were incorporated using thiophene (PtTIC ()), thieno[3,2-]thiophene (PtT2IC ()), and 4-cyclopenta[2,1-:3,4-']dithiophene (PtCDTIC ()) as the acetylide donor units. Single-crystal X-ray diffractometry analysis revealed translinear platinum-acetylide complexation in all cases. The strong (═O···S) interactions between the oxygen atoms of the indene acceptor units and the sulfur atoms of the thiophene-derived donor units induced a highly planar orientation among the heterocyclic ligands, featuring π-π interactions between the planes.
View Article and Find Full Text PDFJ Org Chem
December 2024
Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.
Aqueous solubilization of porphyrins, often accomplished with appended polar aryl groups, can also be achieved with symmetrically branched alkyl (i.e., swallowtail) groups terminated with polar moieties.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Department of Physics, School of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Astrocytes respond to neurotransmitters by increasing their intracellular Ca2+ concentration (Ca2+ signals). While glutamate released by neurons trigger Ca2+ signals through IP3- and glutamate transporter-dependent mechanisms, dopamine released in distant sites activates astrocytes via dopaminergic receptors. However, little is known about the modulatory effects of dopamine on glutamate-evoked astrocytic activity.
View Article and Find Full Text PDFMater Horiz
December 2024
School of Energy and Chemical Engineering, UNIST, Ulsan 44919, Korea.
A Zn-coordinated porphyrinic artificial solid-electrolyte interphase (αSEI) layer, named [Zn]PP-4COO-(Zn), was developed to improve the reversibility of zinc metal plating/stripping in aqueous zinc-ion batteries (ZIBs). Inspired by nitrogen-terminating sites of biological molecules coordinating and transporting zinc in zinc metabolic processes, the αSEI layer was designed with zinc ions connecting porphyrinic building blocks to form two-dimensional clathrate sheets and stacking -plane sheets along the -axis to allow N cages to align and form porphyrinic N channels for zinc transport. The [Zn]PP-4COO-(Zn) αSEI layer was Zn-conductive and structurally durable during repeated stripping/plating.
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