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http://dx.doi.org/10.4103/aian.aian_455_22 | DOI Listing |
Chem Asian J
December 2024
Govt. Degree College for Men, Srikakulam, Department of Chemistry, Srikakulam, 532001, Srikakulam, INDIA.
The production of enantiomerically pure compounds remains a vital and valuable objective in modern organic chemistry due to their broad applications in fields such as biosensing, optics, electronics, photonics, catalysis, nanotechnology, and drug or DNA delivery. Optically pure α-hydroxy ketones, in particular, are key structural components in many drugs and natural products with significant biological activity. Among these, benzoin type α-hydroxy ketones, which possess two adjacent functional groups, a carbonyl and a hydroxy group, are especially important.
View Article and Find Full Text PDFNucl Med Commun
November 2024
Institute of Nuclear Medicine, University College London Hospital, University College London Hospitals NHS Foundation Trust (UCLH), .
Ann Surg Oncol
October 2024
Department of Surgery, University of California San Diego, San Diego, CA, USA.
J Relig Health
December 2023
School of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD, Australia.
J Am Chem Soc
August 2023
The GlaxoSmithKline Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Jubilee Campus, Triumph Road, Nottingham, NG7 2TU, United Kingdom.
Bridged or caged polycyclic hydrocarbons have rigid structures that project substituents into precise regions of 3D space, making them attractive as linking groups in materials science and as building blocks for medicinal chemistry. The efficient synthesis of new or underexplored classes of such compounds is, therefore, an important objective. Herein, we describe the silver(I)-catalyzed rearrangement of 1,4-disubstituted cubanes to cuneanes, which are strained hydrocarbons that have not received much attention since they were first described in 1970.
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