Multimodal imaging including swept source optical coherence tomography angiography in a case with sclerochoroidal calcification.

Photodiagnosis Photodyn Ther

Department of Ophthalmology, Faculty of Medicine, Ankara University, Dikimevi, Ankara 06590, Turkey; Private Eye Clinic, Farilya Business Center 8/38, Ufuk Universitesi Cad, Çukurambar, Ankara 06510, Turkey. Electronic address:

Published: December 2022

Purpose: We report a case of idiopathic sclerochoroidal calcification (SCC) evaluated with multimodal imaging including swept source optical coherence tomography angiography (SS-OCTA).

Case Presentation: A 52-year-old man was diagnosed with sclerochoroidal calcification in the left eye. Multimodal imaging revealed mixed hypoautofluorescence and hyperautofluorescence on fundus autofluorescence (FAF) imaging; an acoustically solid lesion with hyperreflective deposits on ultrasonography (USG); a rocky configuration with marked disruption of outer retinal layers and abrupt transition from normal to tumor tissue on swept source optical coherence tomography (SS-OCT); hyporeflective plexus in the outer retinal and choroidal slabs and a retinochoroidal shunt vessel on SS-OCTA; and central hypofluorescence with intervening patchy hyperfluorescent areas, diffuse peripheral window defects, and a retinochoroidal shunt vessel on fluorescein angiography (FA). Systemic evaluation including serum parathyroid hormone, calcium, phosphorus, albumin levels, and urine analysis were normal.

Conclusion: Sclerochoroidal calcification is a rare ocular tumor that may be idiopathic or secondary to several nephrological or endocrinological diseases involving calcium and phosphorus mechanism. Multimodal imaging with FAF, USG, OCT, OCTA, and FA help to identify the distinguishing features of the tumor and differentiate it from other entities.

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http://dx.doi.org/10.1016/j.pdpdt.2022.103054DOI Listing

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