Shedding light on immune suppression at high temperature.

Trends Microbiol

National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi, India; Department of Plant Sciences, University of Hyderabad, Hyderabad, Telangana, India. Electronic address:

Published: October 2022

Rising temperatures pose a threat to agriculture in the present times. Salicylic acid (SA) accumulation and signaling is repressed at high temperatures leading to a compromise in plant immunity against pathogens. The mechanism behind this suppression was unknown. Recent evidence from Kim et al. suggests that CBP60g transcription is the key thermosensitive step.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tim.2022.07.010DOI Listing

Publication Analysis

Top Keywords

shedding light
4
light immune
4
immune suppression
4
suppression high
4
high temperature
4
temperature rising
4
rising temperatures
4
temperatures pose
4
pose threat
4
threat agriculture
4

Similar Publications

Bi+ men are more likely to use alcohol and drugs than heterosexual and often gay men. The minority stress model is the predominant framework for understanding these disparities, but it is unknown whether this framework is consistent with bi+ men's perspectives. As part of an online survey, 69 bi+ young men (ages 18-29; 29% transgender) were asked why they think bisexual men are more likely to use alcohol and drugs than other men (including gay men).

View Article and Find Full Text PDF

Visible light-driven pyridoxal radical biocatalysis has emerged as a new strategy for the stereoselective synthesis of valuable noncanonical amino acids in a protecting-group-free fashion. In our previously developed dehydroxylative C-C coupling using engineered PLP-dependent tryptophan synthases, an enzyme-controlled unusual α-stereochemistry reversal and pH-controlled enantiopreference were observed. Herein, through high-throughput photobiocatalysis, we evolved a set of stereochemically complementary PLP radical enzymes, allowing the synthesis of both l- and d-amino acids with enhanced enantiocontrol across a broad pH window.

View Article and Find Full Text PDF

Validating thermodynamic models is essential in experimental geosciences for exploring increasingly complex systems and developing analytical protocols. However, investigating solid-fluid equilibria in mm-sized experimental capsules poses several challenges, particularly in sulfur-bearing chemical systems. These include maintaining bulk fluid composition and performing quantitative analysis with extremely low amounts of synthesized fluid.

View Article and Find Full Text PDF

Acyl-CoA oxidase 1 (ACOX1), a member of the acyl-coenzyme A oxidase family, is considered a crucial regulator whose dysregulation is implicated in the occurrence and progression of various cancers. This study aims to elucidate the impact of ACOX1 in CRC, shedding light on its potential as a therapeutic target. Through analysis of the GEO dataset, it was found that ACOX1 is significantly downregulated in colorectal cancer (CRC), and this lower expression level is associated with a worse prognosis.

View Article and Find Full Text PDF

Piper longum, commonly known as long pepper, is highly valued for its bioactive alkaloid piperine, which has diverse pharmaceutical and culinary applications. In this study, we used high-throughput sequencing and de novo transcriptome assembly to analyze the transcriptomes of P. longum leaves, roots, and spikes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!