Two new antimicrobial monoterpenoid indole alkaloids from the roots of .

J Asian Nat Prod Res

School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.

Published: May 2023

Two new monoterpenoid indole alkaloids 3-hydroxylochnerine () and 10-hydroxyvinorine () were isolated from the roots of . Their structures were elucidated based on the analysis of spectroscopic data and ECD calculation. Both compounds exhibited potent antimicrobial activity against and , and their activities were comparable to the well-known antibacterial drug berberine.

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http://dx.doi.org/10.1080/10286020.2022.2104258DOI Listing

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