A retrospective study of 52 consecutive patients was conducted to determine the influence of certain factors on the ambulatory rehabilitation of patients with hemiplegia and lower extremity amputation. Factors studied included side of hemiplegia, laterality of disability, level of amputation, order of disability (amputation first or hemiplegia first), neuromuscular status, mental status, sex, age. The level of function was defined as independent, limited, or nonambulatory. Of 52 double-disability patients, thirty were fitted with a prosthesis. Eight patients attained independent prosthetic function while 16 patients were limited and six were nonambulatory. Factors such as ipsilateral BK amputation preceding hemiplegia, a good-to-fair neuromuscular status, and an intact mental status have been associated with better functional results. Although producing higher fitting rates, none of these factors has been found in the present study to be associated with statistically higher levels of ambulatory function. A good-to-fair neuromuscular status seemed to be the prime requisite for good ambulation with a prosthesis in a patient with the double disability of amputation and hemiplegia.
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Behav Neurol
January 2025
Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Multiple sclerosis (MS) is the most common cause of disability in young adults due to several motor, sensory, and cognitive symptoms. However, little is still known about the impact of psychological, cognitive, and social-support variables on subjective disability. This study is aimed at exploring the role of clinical, psychological, cognitive, and social-support variables in predicting disability levels as perceived by persons with multiple sclerosis (pwMS).
View Article and Find Full Text PDFApproximately 800,000 total knee arthroplasties and 450,000 total hip arthroplasties are performed annually in the United States. These procedures provide significant pain relief and restore function in patients with advanced osteoarthritis, rheumatoid arthritis, and other degenerative joint conditions. Patient evaluation before surgery includes a history, physical examination, laboratory tests, and imaging.
View Article and Find Full Text PDFPathology
December 2024
Department of Neuropathology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, India. Electronic address:
Neuropathology has been in existence as a speciality in India since the 1950s. Its practice has kept pace with the developments in the field, paralleling advancements in neurosurgery and neurosciences, especially in tertiary care centres. This nationwide survey, conducted across 52 centres, provides a comprehensive analysis of diagnostic infrastructure, training opportunities, and challenges in the practice of neuropathology.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Youth Physical Development Centre, Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Background: Residual interlimb deficits after anterior cruciate ligament reconstruction (ACLR) can lead to functional maladaptation and increase the risk of reinjury. The tuck jump assessment (TJA) may offer a more effective evaluation of ACLR status as compared with traditional tasks owing to increased risk of altered landing mechanics, asymmetrical landing, and increased knee valgus attributed to the cyclical nature of the task. However, it remains unclear whether altered TJA kinetics resolve over time or persist through return-to-play phases of rehabilitation.
View Article and Find Full Text PDFNeurology
February 2025
Division of Clinical and Metabolic Genetics, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
Pathogenic variants in cause congenital muscular dystrophy through hypoglycosylation of alpha-dystroglycan (OMIM #615350). The established phenotypic spectrum of GMPPB-related disorders includes recurrent rhabdomyolysis, limb-girdle muscular dystrophy, neuromuscular transmission abnormalities, and congenital muscular dystrophy with variable brain and eye anomalies. We report a 9-month-old male infant with congenital muscular dystrophy, infantile spasms, and compound heterozygous pathogenic variants (c.
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