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Is extremely low frequency pulsed electromagnetic fields applicable to gliomas? A literature review of the underlying mechanisms and application of extremely low frequency pulsed electromagnetic fields. | LitMetric

AI Article Synopsis

  • * ELF-PEMF is a low-frequency magnetic field with minimal side effects, but its use in glioma treatment is uncommon.
  • * The review discusses five key mechanisms of ELF-PEMF in glioma therapy and explores its potential alongside traditional treatments, offering insights for oncologists.*

Article Abstract

Gliomas refer to a group of complicated human brain tumors with a low 5-year survival rate and limited therapeutic options. Extremely low-frequency pulsed electromagnetic field (ELF-PEMF) is a specific magnetic field featuring almost no side effects. However, the application of ELF-PEMF in the treatment of gliomas is rare. This review summarizes five significant underlying mechanisms including calcium ions, autophagy, apoptosis, angiogenesis, and reactive oxygen species, and applications of ELF-PEMF in glioma treatment from a clinical practice perspective. In addition, the prospects of ELF-PEMF in combination with conventional therapy for the treatment of gliomas are reviewed. This review benefits any specialists, especially oncologists, interested in this new therapy because it can help treat patients with gliomas properly.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939155PMC
http://dx.doi.org/10.1002/cam4.5112DOI Listing

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